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Anti-RNAS4/ RNASE4/ RAB1 functional antibody
Anti-RNAS4/ RNASE4/ RAB1 functional antibody for cell culture, ELISA & in-vivo assay
Go to RNASE4/RNASE4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0448-Ab-1/ GM-Tg-hg-SE0448-Ab-2 | Anti-Human RNASE4 monoclonal antibody | Human |
| GM-Tg-rg-SE0448-Ab-1/ GM-Tg-rg-SE0448-Ab-2 | Anti-Rat RNASE4 monoclonal antibody | Rat |
| GM-Tg-mg-SE0448-Ab-1/ GM-Tg-mg-SE0448-Ab-2 | Anti-Mouse RNASE4 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0448-Ab-1/ GM-Tg-cynog-SE0448-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RNASE4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0448-Ab-1/ GM-Tg-felg-SE0448-Ab-2 | Anti-Feline RNASE4 monoclonal antibody | Feline |
| GM-Tg-cang-SE0448-Ab-1/ GM-Tg-cang-SE0448-Ab-2 | Anti-Canine RNASE4 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0448-Ab-1/ GM-Tg-bovg-SE0448-Ab-2 | Anti-Bovine RNASE4 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0448-Ab-1/ GM-Tg-equg-SE0448-Ab-2 | Anti-Equine RNASE4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0448-Ab-1/ GM-Tg-hg-SE0448-Ab-2; GM-Tg-rg-SE0448-Ab-1/ GM-Tg-rg-SE0448-Ab-2; GM-Tg-mg-SE0448-Ab-1/ GM-Tg-mg-SE0448-Ab-2; GM-Tg-cynog-SE0448-Ab-1/ GM-Tg-cynog-SE0448-Ab-2; GM-Tg-felg-SE0448-Ab-1/ GM-Tg-felg-SE0448-Ab-2; GM-Tg-cang-SE0448-Ab-1/ GM-Tg-cang-SE0448-Ab-2; GM-Tg-bovg-SE0448-Ab-1/ GM-Tg-bovg-SE0448-Ab-2; GM-Tg-equg-SE0448-Ab-1/ GM-Tg-equg-SE0448-Ab-2 |
| Products Name | Anti-RNASE4 monoclonal antibody |
| Format | mab |
| Target Name | RNASE4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RNASE4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0448-Ag-1 | Recombinant multi-species RNAS4/ RNASE4/ RAB1 protein |
| ORF Viral Vector | vGMLP004155 | human RNASE4 Lentivirus particle |
| ORF Viral Vector | pGMLP004155 | human RNASE4 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004144 | mouse Rnase4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004144 | mouse Rnase4 Lentivirus particle |
Target information
| Target ID | GM-SE0448 |
| Target Name | RNASE4 |
| Gene ID | 6038,58809,56759,102900763,616089,106780845 |
| Gene Symbol and Synonyms | C730049F20Rik,RAB1,RNASE4,RNS4 |
| Uniprot Accession | P34096,O55004,P15467 |
| Uniprot Entry Name | RNAS4_HUMAN,RNAS4_RAT,RNAS4_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000258818 |
| Target Classification | N/A |
The target: RNASE4, gene name: RNASE4, also named as RAB1, RNS4. The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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