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Anti-ISK13/ SPINK13/ HBVDNAPTP1 functional antibody
Anti-ISK13/ SPINK13/ HBVDNAPTP1 functional antibody for cell culture, ELISA & in-vivo assay
Go to SPINK13/SPINK13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0480-Ab-1/ GM-Tg-hg-SE0480-Ab-2 | Anti-Human SPINK13 monoclonal antibody | Human |
| GM-Tg-rg-SE0480-Ab-1/ GM-Tg-rg-SE0480-Ab-2 | Anti-Rat SPINK13 monoclonal antibody | Rat |
| GM-Tg-mg-SE0480-Ab-1/ GM-Tg-mg-SE0480-Ab-2 | Anti-Mouse SPINK13 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0480-Ab-1/ GM-Tg-cynog-SE0480-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SPINK13 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0480-Ab-1/ GM-Tg-felg-SE0480-Ab-2 | Anti-Feline SPINK13 monoclonal antibody | Feline |
| GM-Tg-cang-SE0480-Ab-1/ GM-Tg-cang-SE0480-Ab-2 | Anti-Canine SPINK13 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0480-Ab-1/ GM-Tg-bovg-SE0480-Ab-2 | Anti-Bovine SPINK13 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0480-Ab-1/ GM-Tg-equg-SE0480-Ab-2 | Anti-Equine SPINK13 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0480-Ab-1/ GM-Tg-hg-SE0480-Ab-2; GM-Tg-rg-SE0480-Ab-1/ GM-Tg-rg-SE0480-Ab-2; GM-Tg-mg-SE0480-Ab-1/ GM-Tg-mg-SE0480-Ab-2; GM-Tg-cynog-SE0480-Ab-1/ GM-Tg-cynog-SE0480-Ab-2; GM-Tg-felg-SE0480-Ab-1/ GM-Tg-felg-SE0480-Ab-2; GM-Tg-cang-SE0480-Ab-1/ GM-Tg-cang-SE0480-Ab-2; GM-Tg-bovg-SE0480-Ab-1/ GM-Tg-bovg-SE0480-Ab-2; GM-Tg-equg-SE0480-Ab-1/ GM-Tg-equg-SE0480-Ab-2 |
| Products Name | Anti-SPINK13 monoclonal antibody |
| Format | mab |
| Target Name | SPINK13 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SPINK13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0480-Ag-1 | Recombinant multi-species ISK13/ SPINK13/ HBVDNAPTP1 protein |
| ORF Viral Vector | pGMLP004365 | human SPINK13 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004365 | human SPINK13 Lentivirus particle |
| ORF Viral Vector | pGMLPm003297 | mouse Spink13 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003297 | mouse Spink13 Lentivirus particle |
Target information
| Target ID | GM-SE0480 |
| Target Name | SPINK13 |
| Gene ID | 153218,100038417,689570,100329159,104972860 |
| Gene Symbol and Synonyms | Gm10534,HBVDNAPTP1,HESPINTOR,LiESP6,SPINK13,SPINK5L3 |
| Uniprot Accession | Q1W4C9,D3ZVP0 |
| Uniprot Entry Name | ISK13_HUMAN,ISK13_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000214510 |
| Target Classification | N/A |
The target: SPINK13, gene name: SPINK13, also named as HBVDNAPTP1, HESPINTOR, LiESP6, SPINK5L3. Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of acrosome reaction. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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