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Anti-TOR2X/ TOR2A/ TOR2A functional antibody
Anti-TOR2X/ TOR2A/ TOR2A functional antibody for cell culture, ELISA & in-vivo assay
Go to TOR2A/TOR2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0522-Ab-1/ GM-Tg-hg-SE0522-Ab-2 | Anti-Human TOR2A monoclonal antibody | Human |
| GM-Tg-rg-SE0522-Ab-1/ GM-Tg-rg-SE0522-Ab-2 | Anti-Rat TOR2A monoclonal antibody | Rat |
| GM-Tg-mg-SE0522-Ab-1/ GM-Tg-mg-SE0522-Ab-2 | Anti-Mouse TOR2A monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0522-Ab-1/ GM-Tg-cynog-SE0522-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TOR2A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0522-Ab-1/ GM-Tg-felg-SE0522-Ab-2 | Anti-Feline TOR2A monoclonal antibody | Feline |
| GM-Tg-cang-SE0522-Ab-1/ GM-Tg-cang-SE0522-Ab-2 | Anti-Canine TOR2A monoclonal antibody | Canine |
| GM-Tg-bovg-SE0522-Ab-1/ GM-Tg-bovg-SE0522-Ab-2 | Anti-Bovine TOR2A monoclonal antibody | Bovine |
| GM-Tg-equg-SE0522-Ab-1/ GM-Tg-equg-SE0522-Ab-2 | Anti-Equine TOR2A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0522-Ab-1/ GM-Tg-hg-SE0522-Ab-2; GM-Tg-rg-SE0522-Ab-1/ GM-Tg-rg-SE0522-Ab-2; GM-Tg-mg-SE0522-Ab-1/ GM-Tg-mg-SE0522-Ab-2; GM-Tg-cynog-SE0522-Ab-1/ GM-Tg-cynog-SE0522-Ab-2; GM-Tg-felg-SE0522-Ab-1/ GM-Tg-felg-SE0522-Ab-2; GM-Tg-cang-SE0522-Ab-1/ GM-Tg-cang-SE0522-Ab-2; GM-Tg-bovg-SE0522-Ab-1/ GM-Tg-bovg-SE0522-Ab-2; GM-Tg-equg-SE0522-Ab-1/ GM-Tg-equg-SE0522-Ab-2 |
| Products Name | Anti-TOR2A monoclonal antibody |
| Format | mab |
| Target Name | TOR2A |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TOR2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0522-Ag-1 | Recombinant multi-species TOR2X/ TOR2A/ TOR2A protein |
| ORF Viral Vector | pGMLP001854 | human Tor2a Lentivirus plasmid |
| ORF Viral Vector | vGMLP001854 | human Tor2a Lentivirus particle |
| ORF Viral Vector | pGMLPm000873 | mouse Tor2a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000873 | mouse Tor2a Lentivirus particle |
Target information
| Target ID | GM-SE0522 |
| Target Name | TOR2A |
| Gene ID | 27433,30933,362112,700203,609191,101092305,534311,100070462 |
| Gene Symbol and Synonyms | Prosalusin,TOR2A,TORP1,Torsin-2A |
| Uniprot Accession | Q8N2E6, Q5JU69,Q6AYR4,A4FUH1,P0C7W1 |
| Uniprot Entry Name | TOR2A_HUMAN,TOR2A_RAT,TOR2A_BOVIN,TOR2X_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000160404 |
| Target Classification | N/A |
The target: TOR2A, gene name: TOR2A, also named as TORP1. This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. The antimicrobial peptide salusin-beta has antibacterial activity. [provided by RefSeq, Nov 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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