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Anti-TBA4A/ TUBA4A/ ALS22 functional antibody
Anti-TBA4A/ TUBA4A/ ALS22 functional antibody for cell culture, ELISA & in-vivo assay
Go to TUBA4A/TUBA4A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0528-Ab-1/ GM-Tg-hg-SE0528-Ab-2 | Anti-Human TUBA4A monoclonal antibody | Human |
| GM-Tg-rg-SE0528-Ab-1/ GM-Tg-rg-SE0528-Ab-2 | Anti-Rat TUBA4A monoclonal antibody | Rat |
| GM-Tg-mg-SE0528-Ab-1/ GM-Tg-mg-SE0528-Ab-2 | Anti-Mouse TUBA4A monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0528-Ab-1/ GM-Tg-cynog-SE0528-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TUBA4A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0528-Ab-1/ GM-Tg-felg-SE0528-Ab-2 | Anti-Feline TUBA4A monoclonal antibody | Feline |
| GM-Tg-cang-SE0528-Ab-1/ GM-Tg-cang-SE0528-Ab-2 | Anti-Canine TUBA4A monoclonal antibody | Canine |
| GM-Tg-bovg-SE0528-Ab-1/ GM-Tg-bovg-SE0528-Ab-2 | Anti-Bovine TUBA4A monoclonal antibody | Bovine |
| GM-Tg-equg-SE0528-Ab-1/ GM-Tg-equg-SE0528-Ab-2 | Anti-Equine TUBA4A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0528-Ab-1/ GM-Tg-hg-SE0528-Ab-2; GM-Tg-rg-SE0528-Ab-1/ GM-Tg-rg-SE0528-Ab-2; GM-Tg-mg-SE0528-Ab-1/ GM-Tg-mg-SE0528-Ab-2; GM-Tg-cynog-SE0528-Ab-1/ GM-Tg-cynog-SE0528-Ab-2; GM-Tg-felg-SE0528-Ab-1/ GM-Tg-felg-SE0528-Ab-2; GM-Tg-cang-SE0528-Ab-1/ GM-Tg-cang-SE0528-Ab-2; GM-Tg-bovg-SE0528-Ab-1/ GM-Tg-bovg-SE0528-Ab-2; GM-Tg-equg-SE0528-Ab-1/ GM-Tg-equg-SE0528-Ab-2 |
| Products Name | Anti-TUBA4A monoclonal antibody |
| Format | mab |
| Target Name | TUBA4A |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TUBA4A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0528-Ag-1 | Recombinant multi-species TBA4A/ TUBA4A/ ALS22 protein |
| ORF Viral Vector | vGMLP000268 | human TUBA4A Lentivirus particle |
| ORF Viral Vector | pGMLP000268 | human TUBA4A Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004918 | mouse Tuba4a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004918 | mouse Tuba4a Lentivirus particle |
Target information
| Target ID | GM-SE0528 |
| Target Name | TUBA4A |
| Gene ID | 7277,316531,702583,101095277,777775,100059249 |
| Gene Symbol and Synonyms | ALS22,H2-ALPHA,TUBA1,Tuba4,TUBA4A |
| Uniprot Accession | P68366,Q5XIF6,P81948 |
| Uniprot Entry Name | TBA4A_HUMAN,TBA4A_RAT,TBA4A_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000127824 |
| Target Classification | N/A |
The target: TUBA4A, gene name: TUBA4A, also named as ALS22, H2-ALPHA, TUBA1. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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