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Anti-UCN2/ SRP/ UCN-II functional antibody
Anti-UCN2/ SRP/ UCN-II functional antibody for cell culture, ELISA & in-vivo assay
Go to UCN2/UCN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0533-Ab-1/ GM-Tg-hg-SE0533-Ab-2 | Anti-Human UCN2 monoclonal antibody | Human |
| GM-Tg-rg-SE0533-Ab-1/ GM-Tg-rg-SE0533-Ab-2 | Anti-Rat UCN2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0533-Ab-1/ GM-Tg-mg-SE0533-Ab-2 | Anti-Mouse UCN2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0533-Ab-1/ GM-Tg-cynog-SE0533-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UCN2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0533-Ab-1/ GM-Tg-felg-SE0533-Ab-2 | Anti-Feline UCN2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0533-Ab-1/ GM-Tg-cang-SE0533-Ab-2 | Anti-Canine UCN2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0533-Ab-1/ GM-Tg-bovg-SE0533-Ab-2 | Anti-Bovine UCN2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0533-Ab-1/ GM-Tg-equg-SE0533-Ab-2 | Anti-Equine UCN2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0533-Ab-1/ GM-Tg-hg-SE0533-Ab-2; GM-Tg-rg-SE0533-Ab-1/ GM-Tg-rg-SE0533-Ab-2; GM-Tg-mg-SE0533-Ab-1/ GM-Tg-mg-SE0533-Ab-2; GM-Tg-cynog-SE0533-Ab-1/ GM-Tg-cynog-SE0533-Ab-2; GM-Tg-felg-SE0533-Ab-1/ GM-Tg-felg-SE0533-Ab-2; GM-Tg-cang-SE0533-Ab-1/ GM-Tg-cang-SE0533-Ab-2; GM-Tg-bovg-SE0533-Ab-1/ GM-Tg-bovg-SE0533-Ab-2; GM-Tg-equg-SE0533-Ab-1/ GM-Tg-equg-SE0533-Ab-2 |
| Products Name | Anti-UCN2 monoclonal antibody |
| Format | mab |
| Target Name | UCN2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-UCN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0533-Ag-1 | Recombinant multi-species UCN2/ SRP/ UCN-II protein |
| ORF Viral Vector | pGMLP000406 | human UCN2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000406 | human UCN2 Lentivirus particle |
| ORF Viral Vector | pGMLPm003755 | mouse Ucn2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003755 | mouse Ucn2 Lentivirus particle |
Target information
| Target ID | GM-SE0533 |
| Target Name | UCN2 |
| Gene ID | 90226,171530,170896,106996925,100683848,101088991,751828 |
| Gene Symbol and Synonyms | SRP,Ucn II,Ucn-2,UCN-II,UCN2,Ucn3,UCNI,UR,URP |
| Uniprot Accession | Q96RP3,Q91WW1 |
| Uniprot Entry Name | UCN2_HUMAN,UCN2_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000145040 |
| Target Classification | N/A |
The target: UCN2, gene name: UCN2, also named as SRP, UCN-II, UCNI, UR, URP. This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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