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Anti-AMBN/ AI1F functional antibody
Anti-AMBN/ AI1F functional antibody for cell culture, ELISA & in-vivo assay
Go to AMBN/AMBN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0658-Ab-1/ GM-Tg-hg-SE0658-Ab-2 | Anti-Human AMBN monoclonal antibody | Human |
| GM-Tg-rg-SE0658-Ab-1/ GM-Tg-rg-SE0658-Ab-2 | Anti-Rat AMBN monoclonal antibody | Rat |
| GM-Tg-mg-SE0658-Ab-1/ GM-Tg-mg-SE0658-Ab-2 | Anti-Mouse AMBN monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0658-Ab-1/ GM-Tg-cynog-SE0658-Ab-2 | Anti-Cynomolgus/ Rhesus macaque AMBN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0658-Ab-1/ GM-Tg-felg-SE0658-Ab-2 | Anti-Feline AMBN monoclonal antibody | Feline |
| GM-Tg-cang-SE0658-Ab-1/ GM-Tg-cang-SE0658-Ab-2 | Anti-Canine AMBN monoclonal antibody | Canine |
| GM-Tg-bovg-SE0658-Ab-1/ GM-Tg-bovg-SE0658-Ab-2 | Anti-Bovine AMBN monoclonal antibody | Bovine |
| GM-Tg-equg-SE0658-Ab-1/ GM-Tg-equg-SE0658-Ab-2 | Anti-Equine AMBN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0658-Ab-1/ GM-Tg-hg-SE0658-Ab-2; GM-Tg-rg-SE0658-Ab-1/ GM-Tg-rg-SE0658-Ab-2; GM-Tg-mg-SE0658-Ab-1/ GM-Tg-mg-SE0658-Ab-2; GM-Tg-cynog-SE0658-Ab-1/ GM-Tg-cynog-SE0658-Ab-2; GM-Tg-felg-SE0658-Ab-1/ GM-Tg-felg-SE0658-Ab-2; GM-Tg-cang-SE0658-Ab-1/ GM-Tg-cang-SE0658-Ab-2; GM-Tg-bovg-SE0658-Ab-1/ GM-Tg-bovg-SE0658-Ab-2; GM-Tg-equg-SE0658-Ab-1/ GM-Tg-equg-SE0658-Ab-2 |
| Products Name | Anti-AMBN monoclonal antibody |
| Format | mab |
| Target Name | AMBN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-AMBN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0658-Ag-1 | Recombinant multi-species AMBN/ AI1F protein |
| ORF Viral Vector | pGMLP001297 | human AMBN Lentivirus plasmid |
| ORF Viral Vector | vGMLP001297 | human AMBN Lentivirus particle |
Target information
| Target ID | GM-SE0658 |
| Target Name | AMBN |
| Gene ID | 258,11698,25376,706845,482185,101096807,280995,100054155 |
| Gene Symbol and Synonyms | AI1F,AMBN |
| Uniprot Accession | Q9NP70,Q62840,Q9XSX7 |
| Uniprot Entry Name | AMBN_HUMAN,AMBN_RAT,AMBN_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000178522 |
| Target Classification | N/A |
The target: AMBN, gene name: AMBN, also named as AI1F. This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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