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Anti-CAP7/ AZU1/ AZAMP functional antibody
Anti-CAP7/ AZU1/ AZAMP functional antibody for cell culture, ELISA & in-vivo assay
Go to AZU1/AZU1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0682-Ab-1/ GM-Tg-hg-SE0682-Ab-2 | Anti-Human AZU1 monoclonal antibody | Human |
| GM-Tg-rg-SE0682-Ab-1/ GM-Tg-rg-SE0682-Ab-2 | Anti-Rat AZU1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0682-Ab-1/ GM-Tg-mg-SE0682-Ab-2 | Anti-Mouse AZU1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0682-Ab-1/ GM-Tg-cynog-SE0682-Ab-2 | Anti-Cynomolgus/ Rhesus macaque AZU1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0682-Ab-1/ GM-Tg-felg-SE0682-Ab-2 | Anti-Feline AZU1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0682-Ab-1/ GM-Tg-cang-SE0682-Ab-2 | Anti-Canine AZU1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0682-Ab-1/ GM-Tg-bovg-SE0682-Ab-2 | Anti-Bovine AZU1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0682-Ab-1/ GM-Tg-equg-SE0682-Ab-2 | Anti-Equine AZU1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0682-Ab-1/ GM-Tg-hg-SE0682-Ab-2; GM-Tg-rg-SE0682-Ab-1/ GM-Tg-rg-SE0682-Ab-2; GM-Tg-mg-SE0682-Ab-1/ GM-Tg-mg-SE0682-Ab-2; GM-Tg-cynog-SE0682-Ab-1/ GM-Tg-cynog-SE0682-Ab-2; GM-Tg-felg-SE0682-Ab-1/ GM-Tg-felg-SE0682-Ab-2; GM-Tg-cang-SE0682-Ab-1/ GM-Tg-cang-SE0682-Ab-2; GM-Tg-bovg-SE0682-Ab-1/ GM-Tg-bovg-SE0682-Ab-2; GM-Tg-equg-SE0682-Ab-1/ GM-Tg-equg-SE0682-Ab-2 |
| Products Name | Anti-AZU1 monoclonal antibody |
| Format | mab |
| Target Name | AZU1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-AZU1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0682-Ag-1 | Recombinant multi-species CAP7/ AZU1/ AZAMP protein |
| ORF Viral Vector | pGMLP004614 | human AZU1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004614 | human AZU1 Lentivirus particle |
Target information
| Target ID | GM-SE0682 |
| Target Name | AZU1 |
| Gene ID | 566,100425740,100336938,100146319 |
| Gene Symbol and Synonyms | AZAMP,AZU,AZU1,CAP37,HBP,hHBP,HUMAZUR,NAZC |
| Uniprot Accession | P20160 |
| Uniprot Entry Name | CAP7_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | N/A |
| Gene Ensembl | ENSG00000172232 |
| Target Classification | N/A |
The target: AZU1, gene name: AZU1, also named as AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC, hHBP. Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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