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Anti-CCL1/ I-309/ P500 functional antibody
Anti-CCL1/ I-309/ P500 functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL1/CCL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0738-Ab-1/ GM-Tg-hg-SE0738-Ab-2 | Anti-Human CCL1 monoclonal antibody | Human |
| GM-Tg-rg-SE0738-Ab-1/ GM-Tg-rg-SE0738-Ab-2 | Anti-Rat CCL1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0738-Ab-1/ GM-Tg-mg-SE0738-Ab-2 | Anti-Mouse CCL1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0738-Ab-1/ GM-Tg-cynog-SE0738-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0738-Ab-1/ GM-Tg-felg-SE0738-Ab-2 | Anti-Feline CCL1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0738-Ab-1/ GM-Tg-cang-SE0738-Ab-2 | Anti-Canine CCL1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0738-Ab-1/ GM-Tg-bovg-SE0738-Ab-2 | Anti-Bovine CCL1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0738-Ab-1/ GM-Tg-equg-SE0738-Ab-2 | Anti-Equine CCL1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0738-Ab-1/ GM-Tg-hg-SE0738-Ab-2; GM-Tg-rg-SE0738-Ab-1/ GM-Tg-rg-SE0738-Ab-2; GM-Tg-mg-SE0738-Ab-1/ GM-Tg-mg-SE0738-Ab-2; GM-Tg-cynog-SE0738-Ab-1/ GM-Tg-cynog-SE0738-Ab-2; GM-Tg-felg-SE0738-Ab-1/ GM-Tg-felg-SE0738-Ab-2; GM-Tg-cang-SE0738-Ab-1/ GM-Tg-cang-SE0738-Ab-2; GM-Tg-bovg-SE0738-Ab-1/ GM-Tg-bovg-SE0738-Ab-2; GM-Tg-equg-SE0738-Ab-1/ GM-Tg-equg-SE0738-Ab-2 |
| Products Name | Anti-CCL1 monoclonal antibody |
| Format | mab |
| Target Name | CCL1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0738-Ag-1 | Recombinant multi-species CCL1/ I-309/ P500 protein |
| Cytokine | GM-Tg-g-SE0738-Ag-1 | chemokine (C-C motif) ligand 1 (CCL1) protein |
| ORF Viral Vector | vGMLP003376 | human CCL1 Lentivirus particle |
| ORF Viral Vector | pGMLP003376 | human CCL1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004660 | mouse Ccl1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004660 | mouse Ccl1 Lentivirus particle |
Target information
| Target ID | GM-SE0738 |
| Target Name | CCL1 |
| Gene ID | 6346,20290,688605,574177,448788,101100011,786156,102150259 |
| Gene Symbol and Synonyms | CCL1,I-309,P500,SCYA1,SISe,Tca-3,TCA3 |
| Uniprot Accession | P22362 |
| Uniprot Entry Name | CCL1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000108702 |
| Target Classification | N/A |
The target: CCL1, gene name: CCL1, also named as I-309, P500, SCYA1, SISe, TCA3. This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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