Anti-CCL27/ ALP/ CTACK functional antibody

Anti-CCL27/ ALP/ CTACK functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CCL27/CCL27 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0747-Ab-1/ GM-Tg-hg-SE0747-Ab-2Anti-Human CCL27 monoclonal antibodyHuman
GM-Tg-rg-SE0747-Ab-1/ GM-Tg-rg-SE0747-Ab-2Anti-Rat CCL27 monoclonal antibodyRat
GM-Tg-mg-SE0747-Ab-1/ GM-Tg-mg-SE0747-Ab-2Anti-Mouse CCL27 monoclonal antibodyMouse
GM-Tg-cynog-SE0747-Ab-1/ GM-Tg-cynog-SE0747-Ab-2Anti-Cynomolgus/ Rhesus macaque CCL27 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0747-Ab-1/ GM-Tg-felg-SE0747-Ab-2Anti-Feline CCL27 monoclonal antibodyFeline
GM-Tg-cang-SE0747-Ab-1/ GM-Tg-cang-SE0747-Ab-2Anti-Canine CCL27 monoclonal antibodyCanine
GM-Tg-bovg-SE0747-Ab-1/ GM-Tg-bovg-SE0747-Ab-2Anti-Bovine CCL27 monoclonal antibodyBovine
GM-Tg-equg-SE0747-Ab-1/ GM-Tg-equg-SE0747-Ab-2Anti-Equine CCL27 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0747-Ab-1/ GM-Tg-hg-SE0747-Ab-2; GM-Tg-rg-SE0747-Ab-1/ GM-Tg-rg-SE0747-Ab-2;
GM-Tg-mg-SE0747-Ab-1/ GM-Tg-mg-SE0747-Ab-2; GM-Tg-cynog-SE0747-Ab-1/ GM-Tg-cynog-SE0747-Ab-2;
GM-Tg-felg-SE0747-Ab-1/ GM-Tg-felg-SE0747-Ab-2; GM-Tg-cang-SE0747-Ab-1/ GM-Tg-cang-SE0747-Ab-2;
GM-Tg-bovg-SE0747-Ab-1/ GM-Tg-bovg-SE0747-Ab-2; GM-Tg-equg-SE0747-Ab-1/ GM-Tg-equg-SE0747-Ab-2
Products NameAnti-CCL27 monoclonal antibody
Formatmab
Target NameCCL27
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CCL27 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0747-Ag-1Recombinant multi-species CCL27/ ALP/ CTACK protein
    CytokineGM-Tg-g-SE0747-Ag-1chemokine (C-C motif) ligand 27 (CCL27) protein
    ORF Viral VectorvGMLP000932human CCL27 Lentivirus particle
    ORF Viral VectorpGMLP000932human CCL27 Lentivirus plasmid
    ORF Viral VectorpGMLPm001158mouse Ccl27a Lentivirus plasmid
    ORF Viral VectorvGMLPm001158mouse Ccl27a Lentivirus particle


    Target information

    Target IDGM-SE0747
    Target NameCCL27
    Gene ID10850,20301,574220,445454,101086511,101902682,102147669
    Gene Symbol and SynonymsALP,CCL27,Ccl27a,CTACK,CTAK,ESKINE,ILC,PESKY,SCYA27,Scya27a
    Uniprot AccessionQ9Y4X3
    Uniprot Entry NameCCL27_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000213927
    Target ClassificationN/A

    The target: CCL27, gene name: CCL27, also named as ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27. This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.