Anti-CGB5/ CGB/ HCG functional antibody
Anti-CGB5/ CGB/ HCG functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0769-Ab-1/ GM-Tg-hg-SE0769-Ab-2 | Anti-Human CGB5 monoclonal antibody | Human |
GM-Tg-rg-SE0769-Ab-1/ GM-Tg-rg-SE0769-Ab-2 | Anti-Rat CGB5 monoclonal antibody | Rat |
GM-Tg-mg-SE0769-Ab-1/ GM-Tg-mg-SE0769-Ab-2 | Anti-Mouse CGB5 monoclonal antibody | Mouse |
GM-Tg-cynog-SE0769-Ab-1/ GM-Tg-cynog-SE0769-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CGB5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0769-Ab-1/ GM-Tg-felg-SE0769-Ab-2 | Anti-Feline CGB5 monoclonal antibody | Feline |
GM-Tg-cang-SE0769-Ab-1/ GM-Tg-cang-SE0769-Ab-2 | Anti-Canine CGB5 monoclonal antibody | Canine |
GM-Tg-bovg-SE0769-Ab-1/ GM-Tg-bovg-SE0769-Ab-2 | Anti-Bovine CGB5 monoclonal antibody | Bovine |
GM-Tg-equg-SE0769-Ab-1/ GM-Tg-equg-SE0769-Ab-2 | Anti-Equine CGB5 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE0769-Ab-1/ GM-Tg-hg-SE0769-Ab-2; GM-Tg-rg-SE0769-Ab-1/ GM-Tg-rg-SE0769-Ab-2; GM-Tg-mg-SE0769-Ab-1/ GM-Tg-mg-SE0769-Ab-2; GM-Tg-cynog-SE0769-Ab-1/ GM-Tg-cynog-SE0769-Ab-2; GM-Tg-felg-SE0769-Ab-1/ GM-Tg-felg-SE0769-Ab-2; GM-Tg-cang-SE0769-Ab-1/ GM-Tg-cang-SE0769-Ab-2; GM-Tg-bovg-SE0769-Ab-1/ GM-Tg-bovg-SE0769-Ab-2; GM-Tg-equg-SE0769-Ab-1/ GM-Tg-equg-SE0769-Ab-2 |
Products Name | Anti-CGB5 monoclonal antibody |
Format | mab |
Target Name | CGB5 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CGB5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE0769-Ag-1 | Recombinant multi-species CGB5/ CGB/ HCG protein |
ORF Viral Vector | pGMAP000226 | Human CGB5 Adenovirus plasmid |
ORF Viral Vector | vGMLP000518 | human CGB5 Lentivirus particle |
ORF Viral Vector | pGMAP000482 | Human CGB5 Adenovirus plasmid |
ORF Viral Vector | vGMAP000482 | Human CGB5 Adenovirus particle |
ORF Viral Vector | pGMLP000518 | human CGB5 Lentivirus plasmid |
ORF Viral Vector | vGMAP000226 | Human CGB5 Adenovirus particle |
Target information
Target ID | GM-SE0769 |
Target Name | CGB5 |
Gene ID | 93659 |
Gene Symbol and Synonyms | CGB,CGB5,HCG,hCGB |
Uniprot Accession | N/A |
Uniprot Entry Name | |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000189052 |
Target Classification | N/A |
The target: CGB5, gene name: CGB5, also named as CGB, HCG, hCGB. This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.