Anti-CGB5/ CGB/ HCG functional antibody

Anti-CGB5/ CGB/ HCG functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CGB5/CGB5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0769-Ab-1/ GM-Tg-hg-SE0769-Ab-2Anti-Human CGB5 monoclonal antibodyHuman
GM-Tg-rg-SE0769-Ab-1/ GM-Tg-rg-SE0769-Ab-2Anti-Rat CGB5 monoclonal antibodyRat
GM-Tg-mg-SE0769-Ab-1/ GM-Tg-mg-SE0769-Ab-2Anti-Mouse CGB5 monoclonal antibodyMouse
GM-Tg-cynog-SE0769-Ab-1/ GM-Tg-cynog-SE0769-Ab-2Anti-Cynomolgus/ Rhesus macaque CGB5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0769-Ab-1/ GM-Tg-felg-SE0769-Ab-2Anti-Feline CGB5 monoclonal antibodyFeline
GM-Tg-cang-SE0769-Ab-1/ GM-Tg-cang-SE0769-Ab-2Anti-Canine CGB5 monoclonal antibodyCanine
GM-Tg-bovg-SE0769-Ab-1/ GM-Tg-bovg-SE0769-Ab-2Anti-Bovine CGB5 monoclonal antibodyBovine
GM-Tg-equg-SE0769-Ab-1/ GM-Tg-equg-SE0769-Ab-2Anti-Equine CGB5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0769-Ab-1/ GM-Tg-hg-SE0769-Ab-2; GM-Tg-rg-SE0769-Ab-1/ GM-Tg-rg-SE0769-Ab-2;
GM-Tg-mg-SE0769-Ab-1/ GM-Tg-mg-SE0769-Ab-2; GM-Tg-cynog-SE0769-Ab-1/ GM-Tg-cynog-SE0769-Ab-2;
GM-Tg-felg-SE0769-Ab-1/ GM-Tg-felg-SE0769-Ab-2; GM-Tg-cang-SE0769-Ab-1/ GM-Tg-cang-SE0769-Ab-2;
GM-Tg-bovg-SE0769-Ab-1/ GM-Tg-bovg-SE0769-Ab-2; GM-Tg-equg-SE0769-Ab-1/ GM-Tg-equg-SE0769-Ab-2
Products NameAnti-CGB5 monoclonal antibody
Formatmab
Target NameCGB5
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CGB5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0769-Ag-1Recombinant multi-species CGB5/ CGB/ HCG protein
    ORF Viral VectorpGMAP000226Human CGB5 Adenovirus plasmid
    ORF Viral VectorvGMLP000518human CGB5 Lentivirus particle
    ORF Viral VectorpGMAP000482Human CGB5 Adenovirus plasmid
    ORF Viral VectorvGMAP000482Human CGB5 Adenovirus particle
    ORF Viral VectorpGMLP000518human CGB5 Lentivirus plasmid
    ORF Viral VectorvGMAP000226Human CGB5 Adenovirus particle


    Target information

    Target IDGM-SE0769
    Target NameCGB5
    Gene ID93659
    Gene Symbol and SynonymsCGB,CGB5,HCG,hCGB
    Uniprot AccessionN/A
    Uniprot Entry Name
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000189052
    Target ClassificationN/A

    The target: CGB5, gene name: CGB5, also named as CGB, HCG, hCGB. This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.