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Anti-DMKN/ UNQ729/ ZD52F10 functional antibody
Anti-DMKN/ UNQ729/ ZD52F10 functional antibody for cell culture, ELISA & in-vivo assay
Go to DMKN/DMKN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0890-Ab-1/ GM-Tg-hg-SE0890-Ab-2 | Anti-Human DMKN monoclonal antibody | Human |
| GM-Tg-rg-SE0890-Ab-1/ GM-Tg-rg-SE0890-Ab-2 | Anti-Rat DMKN monoclonal antibody | Rat |
| GM-Tg-mg-SE0890-Ab-1/ GM-Tg-mg-SE0890-Ab-2 | Anti-Mouse DMKN monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0890-Ab-1/ GM-Tg-cynog-SE0890-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DMKN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0890-Ab-1/ GM-Tg-felg-SE0890-Ab-2 | Anti-Feline DMKN monoclonal antibody | Feline |
| GM-Tg-cang-SE0890-Ab-1/ GM-Tg-cang-SE0890-Ab-2 | Anti-Canine DMKN monoclonal antibody | Canine |
| GM-Tg-bovg-SE0890-Ab-1/ GM-Tg-bovg-SE0890-Ab-2 | Anti-Bovine DMKN monoclonal antibody | Bovine |
| GM-Tg-equg-SE0890-Ab-1/ GM-Tg-equg-SE0890-Ab-2 | Anti-Equine DMKN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0890-Ab-1/ GM-Tg-hg-SE0890-Ab-2; GM-Tg-rg-SE0890-Ab-1/ GM-Tg-rg-SE0890-Ab-2; GM-Tg-mg-SE0890-Ab-1/ GM-Tg-mg-SE0890-Ab-2; GM-Tg-cynog-SE0890-Ab-1/ GM-Tg-cynog-SE0890-Ab-2; GM-Tg-felg-SE0890-Ab-1/ GM-Tg-felg-SE0890-Ab-2; GM-Tg-cang-SE0890-Ab-1/ GM-Tg-cang-SE0890-Ab-2; GM-Tg-bovg-SE0890-Ab-1/ GM-Tg-bovg-SE0890-Ab-2; GM-Tg-equg-SE0890-Ab-1/ GM-Tg-equg-SE0890-Ab-2 |
| Products Name | Anti-DMKN monoclonal antibody |
| Format | mab |
| Target Name | DMKN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DMKN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0890-Ag-1 | Recombinant multi-species DMKN/ UNQ729/ ZD52F10 protein |
| ORF Viral Vector | pGMLP004013 | human ZD52F10 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004013 | human ZD52F10 Lentivirus particle |
| ORF Viral Vector | pGMLPm002046 | mouse Dmkn Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002046 | mouse Dmkn Lentivirus particle |
Target information
| Target ID | GM-SE0890 |
| Target Name | DMKN |
| Gene ID | 93099,73712,361548,718709,476484,101100017,618159,102150590 |
| Gene Symbol and Synonyms | 1110014F24Rik,C130074A08,cI-36,DMKN,RGD1561521,SK30,SK89,UNQ729,ZD52F10 |
| Uniprot Accession | Q6E0U4,A2VE23 |
| Uniprot Entry Name | DMKN_HUMAN,DMKN_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000161249 |
| Target Classification | N/A |
The target: DMKN, gene name: DMKN, also named as UNQ729, ZD52F10. This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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