Anti-FGF16/ FGF-16/ MF4 functional antibody

Anti-FGF16/ FGF-16/ MF4 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to FGF16/FGF16 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0917-Ab-1/ GM-Tg-hg-SE0917-Ab-2Anti-Human FGF16 monoclonal antibodyHuman
GM-Tg-rg-SE0917-Ab-1/ GM-Tg-rg-SE0917-Ab-2Anti-Rat FGF16 monoclonal antibodyRat
GM-Tg-mg-SE0917-Ab-1/ GM-Tg-mg-SE0917-Ab-2Anti-Mouse FGF16 monoclonal antibodyMouse
GM-Tg-cynog-SE0917-Ab-1/ GM-Tg-cynog-SE0917-Ab-2Anti-Cynomolgus/ Rhesus macaque FGF16 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0917-Ab-1/ GM-Tg-felg-SE0917-Ab-2Anti-Feline FGF16 monoclonal antibodyFeline
GM-Tg-cang-SE0917-Ab-1/ GM-Tg-cang-SE0917-Ab-2Anti-Canine FGF16 monoclonal antibodyCanine
GM-Tg-bovg-SE0917-Ab-1/ GM-Tg-bovg-SE0917-Ab-2Anti-Bovine FGF16 monoclonal antibodyBovine
GM-Tg-equg-SE0917-Ab-1/ GM-Tg-equg-SE0917-Ab-2Anti-Equine FGF16 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0917-Ab-1/ GM-Tg-hg-SE0917-Ab-2; GM-Tg-rg-SE0917-Ab-1/ GM-Tg-rg-SE0917-Ab-2;
GM-Tg-mg-SE0917-Ab-1/ GM-Tg-mg-SE0917-Ab-2; GM-Tg-cynog-SE0917-Ab-1/ GM-Tg-cynog-SE0917-Ab-2;
GM-Tg-felg-SE0917-Ab-1/ GM-Tg-felg-SE0917-Ab-2; GM-Tg-cang-SE0917-Ab-1/ GM-Tg-cang-SE0917-Ab-2;
GM-Tg-bovg-SE0917-Ab-1/ GM-Tg-bovg-SE0917-Ab-2; GM-Tg-equg-SE0917-Ab-1/ GM-Tg-equg-SE0917-Ab-2
Products NameAnti-FGF16 monoclonal antibody
Formatmab
Target NameFGF16
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FGF16 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0917-Ag-1Recombinant multi-species FGF16/ FGF-16/ MF4 protein
    CytokineGM-Tg-g-SE0917-Ag-1fibroblast growth factor 16 (FGF16) protein
    ORF Viral VectorvGMLP004959human Fgf16 Lentivirus particle
    ORF Viral VectorpGMLP004959human Fgf16 Lentivirus plasmid
    ORF Viral VectorpGMLPm003722mouse Fgf16 Lentivirus plasmid
    ORF Viral VectorvGMLPm003722mouse Fgf16 Lentivirus particle


    Target information

    Target IDGM-SE0917
    Target NameFGF16
    Gene ID8823,80903,60464,705612,491974,101084778,540758,100071790
    Gene Symbol and SynonymsFGF-16,FGF16,Fgf4c,MF4
    Uniprot AccessionO43320,O54769
    Uniprot Entry NameFGF16_HUMAN,FGF16_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000196468
    Target ClassificationN/A

    The target: FGF16, gene name: FGF16, also named as FGF-16, MF4. This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.