Anti-GALP functional antibody

Anti-GALP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to GALP/GALP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0934-Ab-1/ GM-Tg-hg-SE0934-Ab-2Anti-Human GALP monoclonal antibodyHuman
GM-Tg-rg-SE0934-Ab-1/ GM-Tg-rg-SE0934-Ab-2Anti-Rat GALP monoclonal antibodyRat
GM-Tg-mg-SE0934-Ab-1/ GM-Tg-mg-SE0934-Ab-2Anti-Mouse GALP monoclonal antibodyMouse
GM-Tg-cynog-SE0934-Ab-1/ GM-Tg-cynog-SE0934-Ab-2Anti-Cynomolgus/ Rhesus macaque GALP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0934-Ab-1/ GM-Tg-felg-SE0934-Ab-2Anti-Feline GALP monoclonal antibodyFeline
GM-Tg-cang-SE0934-Ab-1/ GM-Tg-cang-SE0934-Ab-2Anti-Canine GALP monoclonal antibodyCanine
GM-Tg-bovg-SE0934-Ab-1/ GM-Tg-bovg-SE0934-Ab-2Anti-Bovine GALP monoclonal antibodyBovine
GM-Tg-equg-SE0934-Ab-1/ GM-Tg-equg-SE0934-Ab-2Anti-Equine GALP monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0934-Ab-1/ GM-Tg-hg-SE0934-Ab-2; GM-Tg-rg-SE0934-Ab-1/ GM-Tg-rg-SE0934-Ab-2;
GM-Tg-mg-SE0934-Ab-1/ GM-Tg-mg-SE0934-Ab-2; GM-Tg-cynog-SE0934-Ab-1/ GM-Tg-cynog-SE0934-Ab-2;
GM-Tg-felg-SE0934-Ab-1/ GM-Tg-felg-SE0934-Ab-2; GM-Tg-cang-SE0934-Ab-1/ GM-Tg-cang-SE0934-Ab-2;
GM-Tg-bovg-SE0934-Ab-1/ GM-Tg-bovg-SE0934-Ab-2; GM-Tg-equg-SE0934-Ab-1/ GM-Tg-equg-SE0934-Ab-2
Products NameAnti-GALP monoclonal antibody
Formatmab
Target NameGALP
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GALP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0934-Ag-1Recombinant multi-species GALP protein
    ORF Viral VectorpGMLP004967human GALP Lentivirus plasmid
    ORF Viral VectorvGMLP004967human GALP Lentivirus particle
    ORF Viral VectorpGMLPm004571mouse Galp Lentivirus plasmid
    ORF Viral VectorvGMLPm004571mouse Galp Lentivirus particle


    Target information

    Target IDGM-SE0934
    Target NameGALP
    Gene ID85569,232836,64568,704323,102151546,109494653,102150242
    Gene Symbol and SynonymsGAL,GALP
    Uniprot AccessionQ9UBC7,Q9QXQ6
    Uniprot Entry NameGALP_HUMAN,GALP_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197487
    Target ClassificationN/A

    The target: GALP, gene name: GALP, also named as . This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors..



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.