Anti-IN35/ IFI35/ IFP35 functional antibody

Anti-IN35/ IFI35/ IFP35 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to IFI35/IFI35 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0975-Ab-1/ GM-Tg-hg-SE0975-Ab-2Anti-Human IFI35 monoclonal antibodyHuman
GM-Tg-rg-SE0975-Ab-1/ GM-Tg-rg-SE0975-Ab-2Anti-Rat IFI35 monoclonal antibodyRat
GM-Tg-mg-SE0975-Ab-1/ GM-Tg-mg-SE0975-Ab-2Anti-Mouse IFI35 monoclonal antibodyMouse
GM-Tg-cynog-SE0975-Ab-1/ GM-Tg-cynog-SE0975-Ab-2Anti-Cynomolgus/ Rhesus macaque IFI35 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0975-Ab-1/ GM-Tg-felg-SE0975-Ab-2Anti-Feline IFI35 monoclonal antibodyFeline
GM-Tg-cang-SE0975-Ab-1/ GM-Tg-cang-SE0975-Ab-2Anti-Canine IFI35 monoclonal antibodyCanine
GM-Tg-bovg-SE0975-Ab-1/ GM-Tg-bovg-SE0975-Ab-2Anti-Bovine IFI35 monoclonal antibodyBovine
GM-Tg-equg-SE0975-Ab-1/ GM-Tg-equg-SE0975-Ab-2Anti-Equine IFI35 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0975-Ab-1/ GM-Tg-hg-SE0975-Ab-2; GM-Tg-rg-SE0975-Ab-1/ GM-Tg-rg-SE0975-Ab-2;
GM-Tg-mg-SE0975-Ab-1/ GM-Tg-mg-SE0975-Ab-2; GM-Tg-cynog-SE0975-Ab-1/ GM-Tg-cynog-SE0975-Ab-2;
GM-Tg-felg-SE0975-Ab-1/ GM-Tg-felg-SE0975-Ab-2; GM-Tg-cang-SE0975-Ab-1/ GM-Tg-cang-SE0975-Ab-2;
GM-Tg-bovg-SE0975-Ab-1/ GM-Tg-bovg-SE0975-Ab-2; GM-Tg-equg-SE0975-Ab-1/ GM-Tg-equg-SE0975-Ab-2
Products NameAnti-IFI35 monoclonal antibody
Formatmab
Target NameIFI35
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IFI35 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0975-Ag-1Recombinant multi-species IN35/ IFI35/ IFP35 protein
    ORF Viral VectorvGMLP004640human IFI35 Lentivirus particle
    ORF Viral VectorpGMLV000853human IFI35 Lentivirus plasmid
    ORF Viral VectorvGMLV000853human IFI35 Lentivirus particle
    ORF Viral VectorpGMLP004640human IFI35 Lentivirus plasmid
    ORF Viral VectorpGMLPm000885mouse Ifi35 Lentivirus plasmid
    ORF Viral VectorvGMLPm000885mouse Ifi35 Lentivirus particle


    Target information

    Target IDGM-SE0975
    Target NameIFI35
    Gene ID3430,70110,287719,712409,490954,101093657,510697,100052050
    Gene Symbol and Synonyms2010008K16Rik,ifi-35,IFI35,IFP35
    Uniprot AccessionP80217
    Uniprot Entry NameIN35_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000068079
    Target ClassificationN/A

    The target: IFI35, gene name: IFI35, also named as IFP35. Enables identical protein binding activity. Involved in several processes, including macrophage activation involved in immune response; positive regulation of defense response; and regulation of signal transduction. Located in several cellular components, including cytosol; extracellular space; and nucleus. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.