Anti-NMS functional antibody

Anti-NMS functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to NMS/NMS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1127-Ab-1/ GM-Tg-hg-SE1127-Ab-2Anti-Human NMS monoclonal antibodyHuman
GM-Tg-rg-SE1127-Ab-1/ GM-Tg-rg-SE1127-Ab-2Anti-Rat NMS monoclonal antibodyRat
GM-Tg-mg-SE1127-Ab-1/ GM-Tg-mg-SE1127-Ab-2Anti-Mouse NMS monoclonal antibodyMouse
GM-Tg-cynog-SE1127-Ab-1/ GM-Tg-cynog-SE1127-Ab-2Anti-Cynomolgus/ Rhesus macaque NMS monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1127-Ab-1/ GM-Tg-felg-SE1127-Ab-2Anti-Feline NMS monoclonal antibodyFeline
GM-Tg-cang-SE1127-Ab-1/ GM-Tg-cang-SE1127-Ab-2Anti-Canine NMS monoclonal antibodyCanine
GM-Tg-bovg-SE1127-Ab-1/ GM-Tg-bovg-SE1127-Ab-2Anti-Bovine NMS monoclonal antibodyBovine
GM-Tg-equg-SE1127-Ab-1/ GM-Tg-equg-SE1127-Ab-2Anti-Equine NMS monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1127-Ab-1/ GM-Tg-hg-SE1127-Ab-2; GM-Tg-rg-SE1127-Ab-1/ GM-Tg-rg-SE1127-Ab-2;
GM-Tg-mg-SE1127-Ab-1/ GM-Tg-mg-SE1127-Ab-2; GM-Tg-cynog-SE1127-Ab-1/ GM-Tg-cynog-SE1127-Ab-2;
GM-Tg-felg-SE1127-Ab-1/ GM-Tg-felg-SE1127-Ab-2; GM-Tg-cang-SE1127-Ab-1/ GM-Tg-cang-SE1127-Ab-2;
GM-Tg-bovg-SE1127-Ab-1/ GM-Tg-bovg-SE1127-Ab-2; GM-Tg-equg-SE1127-Ab-1/ GM-Tg-equg-SE1127-Ab-2
Products NameAnti-NMS monoclonal antibody
Formatmab
Target NameNMS
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NMS benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1127-Ag-1Recombinant multi-species NMS protein
    ORF Viral VectorvGMLP001873human NMS Lentivirus particle
    ORF Viral VectorpGMLP001873human NMS Lentivirus plasmid
    ORF Viral VectorpGMLPm003933mouse Nms Lentivirus plasmid
    ORF Viral VectorpGMLPm003934mouse Nms Lentivirus plasmid
    ORF Viral VectorvGMLPm003933mouse Nms Lentivirus particle
    ORF Viral VectorvGMLPm003934mouse Nms Lentivirus particle


    Target information

    Target IDGM-SE1127
    Target NameNMS
    Gene ID129521,433292,497196,710021,474554,101086135,768331,100630166
    Gene Symbol and SynonymsNMS
    Uniprot AccessionQ5H8A3,Q5H8A2,Q0VBW8
    Uniprot Entry NameNMS_HUMAN,NMS_RAT,NMS_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000204640
    Target ClassificationN/A

    The target: NMS, gene name: NMS, also named as . This gene encodes a member of the neuromedin family of neuropeptides. The encoded preproprotein is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. .



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.