Anti-SAA4/ C-SAA/ CSAA functional antibody

Anti-SAA4/ C-SAA/ CSAA functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SAA4/SAA4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1259-Ab-1/ GM-Tg-hg-SE1259-Ab-2Anti-Human SAA4 monoclonal antibodyHuman
GM-Tg-rg-SE1259-Ab-1/ GM-Tg-rg-SE1259-Ab-2Anti-Rat SAA4 monoclonal antibodyRat
GM-Tg-mg-SE1259-Ab-1/ GM-Tg-mg-SE1259-Ab-2Anti-Mouse SAA4 monoclonal antibodyMouse
GM-Tg-cynog-SE1259-Ab-1/ GM-Tg-cynog-SE1259-Ab-2Anti-Cynomolgus/ Rhesus macaque SAA4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1259-Ab-1/ GM-Tg-felg-SE1259-Ab-2Anti-Feline SAA4 monoclonal antibodyFeline
GM-Tg-cang-SE1259-Ab-1/ GM-Tg-cang-SE1259-Ab-2Anti-Canine SAA4 monoclonal antibodyCanine
GM-Tg-bovg-SE1259-Ab-1/ GM-Tg-bovg-SE1259-Ab-2Anti-Bovine SAA4 monoclonal antibodyBovine
GM-Tg-equg-SE1259-Ab-1/ GM-Tg-equg-SE1259-Ab-2Anti-Equine SAA4 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1259-Ab-1/ GM-Tg-hg-SE1259-Ab-2; GM-Tg-rg-SE1259-Ab-1/ GM-Tg-rg-SE1259-Ab-2;
GM-Tg-mg-SE1259-Ab-1/ GM-Tg-mg-SE1259-Ab-2; GM-Tg-cynog-SE1259-Ab-1/ GM-Tg-cynog-SE1259-Ab-2;
GM-Tg-felg-SE1259-Ab-1/ GM-Tg-felg-SE1259-Ab-2; GM-Tg-cang-SE1259-Ab-1/ GM-Tg-cang-SE1259-Ab-2;
GM-Tg-bovg-SE1259-Ab-1/ GM-Tg-bovg-SE1259-Ab-2; GM-Tg-equg-SE1259-Ab-1/ GM-Tg-equg-SE1259-Ab-2
Products NameAnti-SAA4 monoclonal antibody
Formatmab
Target NameSAA4
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SAA4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1259-Ag-1Recombinant multi-species SAA4/ C-SAA/ CSAA protein
    ORF Viral VectorpGMAAV000264human SAA4 AAV plasmid
    ORF Viral VectorvGMAAV000264human SAA4 AAV particle


    Target information

    Target IDGM-SE1259
    Target NameSAA4
    Gene ID6291,20211,694709
    Gene Symbol and SynonymsC-SAA,CSAA,Saa-4,Saa-5,SAA4
    Uniprot AccessionP35542
    Uniprot Entry NameSAA4_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000148965
    Target ClassificationN/A

    The target: SAA4, gene name: SAA4, also named as C-SAA, CSAA. Predicted to be involved in acute-phase response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.