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Anti-SG1D1/ SCGB1D1/ LIPA functional antibody
Anti-SG1D1/ SCGB1D1/ LIPA functional antibody for cell culture, ELISA & in-vivo assay
Go to SCGB1D1/SCGB1D1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1265-Ab-1/ GM-Tg-hg-SE1265-Ab-2 | Anti-Human SCGB1D1 monoclonal antibody | Human |
| GM-Tg-rg-SE1265-Ab-1/ GM-Tg-rg-SE1265-Ab-2 | Anti-Rat SCGB1D1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1265-Ab-1/ GM-Tg-mg-SE1265-Ab-2 | Anti-Mouse SCGB1D1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1265-Ab-1/ GM-Tg-cynog-SE1265-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SCGB1D1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1265-Ab-1/ GM-Tg-felg-SE1265-Ab-2 | Anti-Feline SCGB1D1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1265-Ab-1/ GM-Tg-cang-SE1265-Ab-2 | Anti-Canine SCGB1D1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1265-Ab-1/ GM-Tg-bovg-SE1265-Ab-2 | Anti-Bovine SCGB1D1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1265-Ab-1/ GM-Tg-equg-SE1265-Ab-2 | Anti-Equine SCGB1D1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1265-Ab-1/ GM-Tg-hg-SE1265-Ab-2; GM-Tg-rg-SE1265-Ab-1/ GM-Tg-rg-SE1265-Ab-2; GM-Tg-mg-SE1265-Ab-1/ GM-Tg-mg-SE1265-Ab-2; GM-Tg-cynog-SE1265-Ab-1/ GM-Tg-cynog-SE1265-Ab-2; GM-Tg-felg-SE1265-Ab-1/ GM-Tg-felg-SE1265-Ab-2; GM-Tg-cang-SE1265-Ab-1/ GM-Tg-cang-SE1265-Ab-2; GM-Tg-bovg-SE1265-Ab-1/ GM-Tg-bovg-SE1265-Ab-2; GM-Tg-equg-SE1265-Ab-1/ GM-Tg-equg-SE1265-Ab-2 |
| Products Name | Anti-SCGB1D1 monoclonal antibody |
| Format | mab |
| Target Name | SCGB1D1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SCGB1D1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1265-Ag-1 | Recombinant multi-species SG1D1/ SCGB1D1/ LIPA protein |
| ORF Viral Vector | vGMLP004668 | human SCGB1D1 Lentivirus particle |
| ORF Viral Vector | pGMLP004668 | human SCGB1D1 Lentivirus plasmid |
Target information
| Target ID | GM-SE1265 |
| Target Name | SCGB1D1 |
| Gene ID | 10648 |
| Gene Symbol and Synonyms | LIPA,LPHA,LPNA,SCGB1D1 |
| Uniprot Accession | O95968 |
| Uniprot Entry Name | SG1D1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000168515 |
| Target Classification | N/A |
The target: SCGB1D1, gene name: SCGB1D1, also named as LIPA, LPHA, LPNA. The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component of a heterodimeric molecule present in human tears whose elution profile is consistent with prostatein, a tetrameric molecule composed of three peptide components in heterodimers. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 15, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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