Anti-SG3A1/ SCGB3A1/ HIN-1 functional antibody

Anti-SG3A1/ SCGB3A1/ HIN-1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SCGB3A1/SCGB3A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1269-Ab-1/ GM-Tg-hg-SE1269-Ab-2Anti-Human SCGB3A1 monoclonal antibodyHuman
GM-Tg-rg-SE1269-Ab-1/ GM-Tg-rg-SE1269-Ab-2Anti-Rat SCGB3A1 monoclonal antibodyRat
GM-Tg-mg-SE1269-Ab-1/ GM-Tg-mg-SE1269-Ab-2Anti-Mouse SCGB3A1 monoclonal antibodyMouse
GM-Tg-cynog-SE1269-Ab-1/ GM-Tg-cynog-SE1269-Ab-2Anti-Cynomolgus/ Rhesus macaque SCGB3A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1269-Ab-1/ GM-Tg-felg-SE1269-Ab-2Anti-Feline SCGB3A1 monoclonal antibodyFeline
GM-Tg-cang-SE1269-Ab-1/ GM-Tg-cang-SE1269-Ab-2Anti-Canine SCGB3A1 monoclonal antibodyCanine
GM-Tg-bovg-SE1269-Ab-1/ GM-Tg-bovg-SE1269-Ab-2Anti-Bovine SCGB3A1 monoclonal antibodyBovine
GM-Tg-equg-SE1269-Ab-1/ GM-Tg-equg-SE1269-Ab-2Anti-Equine SCGB3A1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1269-Ab-1/ GM-Tg-hg-SE1269-Ab-2; GM-Tg-rg-SE1269-Ab-1/ GM-Tg-rg-SE1269-Ab-2;
GM-Tg-mg-SE1269-Ab-1/ GM-Tg-mg-SE1269-Ab-2; GM-Tg-cynog-SE1269-Ab-1/ GM-Tg-cynog-SE1269-Ab-2;
GM-Tg-felg-SE1269-Ab-1/ GM-Tg-felg-SE1269-Ab-2; GM-Tg-cang-SE1269-Ab-1/ GM-Tg-cang-SE1269-Ab-2;
GM-Tg-bovg-SE1269-Ab-1/ GM-Tg-bovg-SE1269-Ab-2; GM-Tg-equg-SE1269-Ab-1/ GM-Tg-equg-SE1269-Ab-2
Products NameAnti-SCGB3A1 monoclonal antibody
Formatmab
Target NameSCGB3A1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SCGB3A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1269-Ag-1Recombinant multi-species SG3A1/ SCGB3A1/ HIN-1 protein
    ORF Viral VectorpGMLP004519human SCGB3A1 Lentivirus plasmid
    ORF Viral VectorvGMLP004519human SCGB3A1 Lentivirus particle
    ORF Viral VectorpGMLPm000280mouse Scgb3a1 Lentivirus plasmid
    ORF Viral VectorvGMLPm000280mouse Scgb3a1 Lentivirus particle


    Target information

    Target IDGM-SE1269
    Target NameSCGB3A1
    Gene ID92304,68662,338418,716331,109492767
    Gene Symbol and SynonymsHIN-1,HIN1,LU105,LuLeu2,PnSP-2,Pnsp2,SCGB3A1,secretoglobin,UGRP2,Utgrp2
    Uniprot AccessionQ96QR1
    Uniprot Entry NameSG3A1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseCancer
    Gene EnsemblENSG00000161055
    Target ClassificationTumor-associated antigen (TAA)

    The target: SCGB3A1, gene name: SCGB3A1, also named as HIN-1, HIN1, LU105, PnSP-2, UGRP2. Predicted to be involved in positive regulation of myoblast fusion. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.