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Anti-SFTA1/ SFTPA1/ COLEC4 functional antibody
Anti-SFTA1/ SFTPA1/ COLEC4 functional antibody for cell culture, ELISA & in-vivo assay
Go to SFTPA1/SFTPA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1287-Ab-1/ GM-Tg-hg-SE1287-Ab-2 | Anti-Human SFTPA1 monoclonal antibody | Human |
| GM-Tg-rg-SE1287-Ab-1/ GM-Tg-rg-SE1287-Ab-2 | Anti-Rat SFTPA1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1287-Ab-1/ GM-Tg-mg-SE1287-Ab-2 | Anti-Mouse SFTPA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1287-Ab-1/ GM-Tg-cynog-SE1287-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SFTPA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1287-Ab-1/ GM-Tg-felg-SE1287-Ab-2 | Anti-Feline SFTPA1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1287-Ab-1/ GM-Tg-cang-SE1287-Ab-2 | Anti-Canine SFTPA1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1287-Ab-1/ GM-Tg-bovg-SE1287-Ab-2 | Anti-Bovine SFTPA1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1287-Ab-1/ GM-Tg-equg-SE1287-Ab-2 | Anti-Equine SFTPA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1287-Ab-1/ GM-Tg-hg-SE1287-Ab-2; GM-Tg-rg-SE1287-Ab-1/ GM-Tg-rg-SE1287-Ab-2; GM-Tg-mg-SE1287-Ab-1/ GM-Tg-mg-SE1287-Ab-2; GM-Tg-cynog-SE1287-Ab-1/ GM-Tg-cynog-SE1287-Ab-2; GM-Tg-felg-SE1287-Ab-1/ GM-Tg-felg-SE1287-Ab-2; GM-Tg-cang-SE1287-Ab-1/ GM-Tg-cang-SE1287-Ab-2; GM-Tg-bovg-SE1287-Ab-1/ GM-Tg-bovg-SE1287-Ab-2; GM-Tg-equg-SE1287-Ab-1/ GM-Tg-equg-SE1287-Ab-2 |
| Products Name | Anti-SFTPA1 monoclonal antibody |
| Format | mab |
| Target Name | SFTPA1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SFTPA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1287-Ag-1 | Recombinant multi-species SFTA1/ SFTPA1/ COLEC4 protein |
| ORF Viral Vector | vGMLP001846 | human SFTPA1 Lentivirus particle |
| ORF Viral Vector | pGMLP001846 | human SFTPA1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000997 | mouse Sftpa1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000997 | mouse Sftpa1 Lentivirus particle |
Target information
| Target ID | GM-SE1287 |
| Target Name | SFTPA1 |
| Gene ID | 653509 |
| Gene Symbol and Synonyms | COLEC4,ILD1,PSAP,PSP-A,PSPA,SFTP1,SFTPA1,SFTPA1B,SP-A,SP-A1,SP-A1 beta,SP-A1 delta,SP-A1 epsilon,SP-A1 gamma,SPA,SPA1 |
| Uniprot Accession | Q8IWL2 |
| Uniprot Entry Name | SFTA1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | N/A |
| Gene Ensembl | ENSG00000122852 |
| Target Classification | N/A |
The target: SFTPA1, gene name: SFTPA1, also named as COLEC4, PSAP, PSP-A, PSPA, SFTP1B, SP-A, SP-A1, SPA, SPA1, SFTPA1. This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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