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Anti-SHBG/ ABP/ SBP functional antibody
Anti-SHBG/ ABP/ SBP functional antibody for cell culture, ELISA & in-vivo assay
Go to SHBG/SHBG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1290-Ab-1/ GM-Tg-hg-SE1290-Ab-2 | Anti-Human SHBG monoclonal antibody | Human |
| GM-Tg-rg-SE1290-Ab-1/ GM-Tg-rg-SE1290-Ab-2 | Anti-Rat SHBG monoclonal antibody | Rat |
| GM-Tg-mg-SE1290-Ab-1/ GM-Tg-mg-SE1290-Ab-2 | Anti-Mouse SHBG monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1290-Ab-1/ GM-Tg-cynog-SE1290-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SHBG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1290-Ab-1/ GM-Tg-felg-SE1290-Ab-2 | Anti-Feline SHBG monoclonal antibody | Feline |
| GM-Tg-cang-SE1290-Ab-1/ GM-Tg-cang-SE1290-Ab-2 | Anti-Canine SHBG monoclonal antibody | Canine |
| GM-Tg-bovg-SE1290-Ab-1/ GM-Tg-bovg-SE1290-Ab-2 | Anti-Bovine SHBG monoclonal antibody | Bovine |
| GM-Tg-equg-SE1290-Ab-1/ GM-Tg-equg-SE1290-Ab-2 | Anti-Equine SHBG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1290-Ab-1/ GM-Tg-hg-SE1290-Ab-2; GM-Tg-rg-SE1290-Ab-1/ GM-Tg-rg-SE1290-Ab-2; GM-Tg-mg-SE1290-Ab-1/ GM-Tg-mg-SE1290-Ab-2; GM-Tg-cynog-SE1290-Ab-1/ GM-Tg-cynog-SE1290-Ab-2; GM-Tg-felg-SE1290-Ab-1/ GM-Tg-felg-SE1290-Ab-2; GM-Tg-cang-SE1290-Ab-1/ GM-Tg-cang-SE1290-Ab-2; GM-Tg-bovg-SE1290-Ab-1/ GM-Tg-bovg-SE1290-Ab-2; GM-Tg-equg-SE1290-Ab-1/ GM-Tg-equg-SE1290-Ab-2 |
| Products Name | Anti-SHBG monoclonal antibody |
| Format | mab |
| Target Name | SHBG |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SHBG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1290-Ag-1 | Recombinant multi-species SHBG/ ABP/ SBP protein |
| ORF Viral Vector | pGMLP003648 | human SHBG Lentivirus plasmid |
| ORF Viral Vector | vGMLP003648 | human SHBG Lentivirus particle |
Target information
| Target ID | GM-SE1290 |
| Target Name | SHBG |
| Gene ID | 6462,20415,24775,716004,100856157,101099508,404182,100073011 |
| Gene Symbol and Synonyms | ABP,Abpa,SBP,SHBG,TEBG |
| Uniprot Accession | P04278,P08689 |
| Uniprot Entry Name | SHBG_HUMAN,SHBG_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Other diseases of intestines (K55-K64) |
| Gene Ensembl | ENSG00000129214 |
| Target Classification | N/A |
The target: SHBG, gene name: SHBG, also named as ABP, SBP, TEBG. This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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