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Anti-TFF2/ SML1/ SP functional antibody
Anti-TFF2/ SML1/ SP functional antibody for cell culture, ELISA & in-vivo assay
Go to TFF2/TFF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1333-Ab-1/ GM-Tg-hg-SE1333-Ab-2 | Anti-Human TFF2 monoclonal antibody | Human |
| GM-Tg-rg-SE1333-Ab-1/ GM-Tg-rg-SE1333-Ab-2 | Anti-Rat TFF2 monoclonal antibody | Rat |
| GM-Tg-mg-SE1333-Ab-1/ GM-Tg-mg-SE1333-Ab-2 | Anti-Mouse TFF2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1333-Ab-1/ GM-Tg-cynog-SE1333-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TFF2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1333-Ab-1/ GM-Tg-felg-SE1333-Ab-2 | Anti-Feline TFF2 monoclonal antibody | Feline |
| GM-Tg-cang-SE1333-Ab-1/ GM-Tg-cang-SE1333-Ab-2 | Anti-Canine TFF2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1333-Ab-1/ GM-Tg-bovg-SE1333-Ab-2 | Anti-Bovine TFF2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1333-Ab-1/ GM-Tg-equg-SE1333-Ab-2 | Anti-Equine TFF2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1333-Ab-1/ GM-Tg-hg-SE1333-Ab-2; GM-Tg-rg-SE1333-Ab-1/ GM-Tg-rg-SE1333-Ab-2; GM-Tg-mg-SE1333-Ab-1/ GM-Tg-mg-SE1333-Ab-2; GM-Tg-cynog-SE1333-Ab-1/ GM-Tg-cynog-SE1333-Ab-2; GM-Tg-felg-SE1333-Ab-1/ GM-Tg-felg-SE1333-Ab-2; GM-Tg-cang-SE1333-Ab-1/ GM-Tg-cang-SE1333-Ab-2; GM-Tg-bovg-SE1333-Ab-1/ GM-Tg-bovg-SE1333-Ab-2; GM-Tg-equg-SE1333-Ab-1/ GM-Tg-equg-SE1333-Ab-2 |
| Products Name | Anti-TFF2 monoclonal antibody |
| Format | mab |
| Target Name | TFF2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TFF2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1333-Ag-1 | Recombinant multi-species TFF2/ SML1/ SP protein |
| ORF Viral Vector | pGMLP002301 | human TFF2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002301 | human TFF2 Lentivirus particle |
| ORF Viral Vector | pGMLPm000578 | mouse Tff2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000578 | mouse Tff2 Lentivirus particle |
Target information
| Target ID | GM-SE1333 |
| Target Name | TFF2 |
| Gene ID | 7032,21785,116592,714550,403489,100170653,616105,100051351 |
| Gene Symbol and Synonyms | mSP,SML1,SP,TFF2 |
| Uniprot Accession | Q03403,Q09030,Q863J2 |
| Uniprot Entry Name | TFF2_HUMAN,TFF2_RAT,TFF2_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | Cancer |
| Gene Ensembl | ENSG00000160181 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: TFF2, gene name: TFF2, also named as SML1, SP. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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