- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-TFF3/ ITF/ P1B functional antibody
Anti-TFF3/ ITF/ P1B functional antibody for cell culture, ELISA & in-vivo assay
Go to TFF3/TFF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1334-Ab-1/ GM-Tg-hg-SE1334-Ab-2 | Anti-Human TFF3 monoclonal antibody | Human |
| GM-Tg-rg-SE1334-Ab-1/ GM-Tg-rg-SE1334-Ab-2 | Anti-Rat TFF3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1334-Ab-1/ GM-Tg-mg-SE1334-Ab-2 | Anti-Mouse TFF3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1334-Ab-1/ GM-Tg-cynog-SE1334-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TFF3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1334-Ab-1/ GM-Tg-felg-SE1334-Ab-2 | Anti-Feline TFF3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1334-Ab-1/ GM-Tg-cang-SE1334-Ab-2 | Anti-Canine TFF3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1334-Ab-1/ GM-Tg-bovg-SE1334-Ab-2 | Anti-Bovine TFF3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1334-Ab-1/ GM-Tg-equg-SE1334-Ab-2 | Anti-Equine TFF3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1334-Ab-1/ GM-Tg-hg-SE1334-Ab-2; GM-Tg-rg-SE1334-Ab-1/ GM-Tg-rg-SE1334-Ab-2; GM-Tg-mg-SE1334-Ab-1/ GM-Tg-mg-SE1334-Ab-2; GM-Tg-cynog-SE1334-Ab-1/ GM-Tg-cynog-SE1334-Ab-2; GM-Tg-felg-SE1334-Ab-1/ GM-Tg-felg-SE1334-Ab-2; GM-Tg-cang-SE1334-Ab-1/ GM-Tg-cang-SE1334-Ab-2; GM-Tg-bovg-SE1334-Ab-1/ GM-Tg-bovg-SE1334-Ab-2; GM-Tg-equg-SE1334-Ab-1/ GM-Tg-equg-SE1334-Ab-2 |
| Products Name | Anti-TFF3 monoclonal antibody |
| Format | mab |
| Target Name | TFF3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TFF3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1334-Ag-1 | Recombinant multi-species TFF3/ ITF/ P1B protein |
| ORF Viral Vector | pGMLP004527 | human TFF3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004527 | human TFF3 Lentivirus particle |
| ORF Viral Vector | pGMLPm000284 | mouse Tff3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000284 | mouse Tff3 Lentivirus particle |
Target information
| Target ID | GM-SE1334 |
| Target Name | TFF3 |
| Gene ID | 7033,21786,25563,722463,403488,100170655,517889,100058018 |
| Gene Symbol and Synonyms | ITF,mITF,P1B,TFF3,TFI |
| Uniprot Accession | Q07654,Q03191,Q863B4,B4X8D9,A8YXX7 |
| Uniprot Entry Name | TFF3_HUMAN,TFF3_RAT,TFF3_FELCA,TFF3_CANLF,TFF3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | Prostate Cancer, Kidney failure |
| Gene Ensembl | ENSG00000160180 |
| Target Classification | N/A |
The target: TFF3, gene name: TFF3, also named as ITF, P1B, TFI. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
