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Anti-HSPB6/ HEL55/ Hsp20 functional antibody
Anti-HSPB6/ HEL55/ Hsp20 functional antibody for cell culture, ELISA & in-vivo assay
Go to HSPB6/HSPB6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1397-Ab-1/ GM-Tg-hg-SE1397-Ab-2 | Anti-Human HSPB6 monoclonal antibody | Human |
| GM-Tg-rg-SE1397-Ab-1/ GM-Tg-rg-SE1397-Ab-2 | Anti-Rat HSPB6 monoclonal antibody | Rat |
| GM-Tg-mg-SE1397-Ab-1/ GM-Tg-mg-SE1397-Ab-2 | Anti-Mouse HSPB6 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1397-Ab-1/ GM-Tg-cynog-SE1397-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HSPB6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1397-Ab-1/ GM-Tg-felg-SE1397-Ab-2 | Anti-Feline HSPB6 monoclonal antibody | Feline |
| GM-Tg-cang-SE1397-Ab-1/ GM-Tg-cang-SE1397-Ab-2 | Anti-Canine HSPB6 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1397-Ab-1/ GM-Tg-bovg-SE1397-Ab-2 | Anti-Bovine HSPB6 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1397-Ab-1/ GM-Tg-equg-SE1397-Ab-2 | Anti-Equine HSPB6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1397-Ab-1/ GM-Tg-hg-SE1397-Ab-2; GM-Tg-rg-SE1397-Ab-1/ GM-Tg-rg-SE1397-Ab-2; GM-Tg-mg-SE1397-Ab-1/ GM-Tg-mg-SE1397-Ab-2; GM-Tg-cynog-SE1397-Ab-1/ GM-Tg-cynog-SE1397-Ab-2; GM-Tg-felg-SE1397-Ab-1/ GM-Tg-felg-SE1397-Ab-2; GM-Tg-cang-SE1397-Ab-1/ GM-Tg-cang-SE1397-Ab-2; GM-Tg-bovg-SE1397-Ab-1/ GM-Tg-bovg-SE1397-Ab-2; GM-Tg-equg-SE1397-Ab-1/ GM-Tg-equg-SE1397-Ab-2 |
| Products Name | Anti-HSPB6 monoclonal antibody |
| Format | mab |
| Target Name | HSPB6 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-HSPB6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1397-Ag-1 | Recombinant multi-species HSPB6/ HEL55/ Hsp20 protein |
| ORF Viral Vector | vGMLP000971 | human HSPB6 Lentivirus particle |
| ORF Viral Vector | pGMLP000971 | human HSPB6 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000257 | mouse Hspb6 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000257 | mouse Hspb6 Lentivirus particle |
Target information
| Target ID | GM-SE1397 |
| Target Name | HSPB6 |
| Gene ID | 126393,243912,192245,710760,484574,101098270,534551,100146605 |
| Gene Symbol and Synonyms | Gm479,HEL55,Hsp20,HSPB6,p20,PPP1R91 |
| Uniprot Accession | O14558,P97541,Q148F8 |
| Uniprot Entry Name | HSPB6_HUMAN,HSPB6_RAT,HSPB6_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000004776 |
| Target Classification | N/A |
The target: HSPB6, gene name: HSPB6, also named as HEL55, Hsp20, PPP1R91. This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation. [provided by RefSeq, Jan 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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