- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-OAS1/ E18/E16/ IFI-4 functional antibody
Anti-OAS1/ E18/E16/ IFI-4 functional antibody for cell culture, ELISA & in-vivo assay
Go to OAS1/OAS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1429-Ab-1/ GM-Tg-hg-SE1429-Ab-2 | Anti-Human OAS1 monoclonal antibody | Human |
| GM-Tg-rg-SE1429-Ab-1/ GM-Tg-rg-SE1429-Ab-2 | Anti-Rat OAS1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1429-Ab-1/ GM-Tg-mg-SE1429-Ab-2 | Anti-Mouse OAS1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1429-Ab-1/ GM-Tg-cynog-SE1429-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OAS1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1429-Ab-1/ GM-Tg-felg-SE1429-Ab-2 | Anti-Feline OAS1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1429-Ab-1/ GM-Tg-cang-SE1429-Ab-2 | Anti-Canine OAS1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1429-Ab-1/ GM-Tg-bovg-SE1429-Ab-2 | Anti-Bovine OAS1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1429-Ab-1/ GM-Tg-equg-SE1429-Ab-2 | Anti-Equine OAS1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1429-Ab-1/ GM-Tg-hg-SE1429-Ab-2; GM-Tg-rg-SE1429-Ab-1/ GM-Tg-rg-SE1429-Ab-2; GM-Tg-mg-SE1429-Ab-1/ GM-Tg-mg-SE1429-Ab-2; GM-Tg-cynog-SE1429-Ab-1/ GM-Tg-cynog-SE1429-Ab-2; GM-Tg-felg-SE1429-Ab-1/ GM-Tg-felg-SE1429-Ab-2; GM-Tg-cang-SE1429-Ab-1/ GM-Tg-cang-SE1429-Ab-2; GM-Tg-bovg-SE1429-Ab-1/ GM-Tg-bovg-SE1429-Ab-2; GM-Tg-equg-SE1429-Ab-1/ GM-Tg-equg-SE1429-Ab-2 |
| Products Name | Anti-OAS1 monoclonal antibody |
| Format | mab |
| Target Name | OAS1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-OAS1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1429-Ag-1 | Recombinant multi-species OAS1/ E18/E16/ IFI-4 protein |
| ORF Viral Vector | vGMLP003646 | human OAS1 Lentivirus particle |
| ORF Viral Vector | pGMLP003646 | human OAS1 Lentivirus plasmid |
Target information
| Target ID | GM-SE1429 |
| Target Name | OAS1 |
| Gene ID | 4938,712265,608778,101087875,100034147 |
| Gene Symbol and Synonyms | E18/E16,IFI-4,IMD100,OAS1,OIAS,OIASI |
| Uniprot Accession | P00973 |
| Uniprot Entry Name | OAS1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000089127 |
| Target Classification | N/A |
The target: OAS1, gene name: OAS1, also named as E18/E16, IFI-4, OIAS, OIASI. This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, May 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
