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Anti-UCP5/ SLC25A14/ BMCP1 functional antibody
Anti-UCP5/ SLC25A14/ BMCP1 functional antibody for cell culture, ELISA & in-vivo assay
Go to SLC25A14/SLC25A14 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1440-Ab-1/ GM-Tg-hg-SE1440-Ab-2 | Anti-Human SLC25A14 monoclonal antibody | Human |
| GM-Tg-rg-SE1440-Ab-1/ GM-Tg-rg-SE1440-Ab-2 | Anti-Rat SLC25A14 monoclonal antibody | Rat |
| GM-Tg-mg-SE1440-Ab-1/ GM-Tg-mg-SE1440-Ab-2 | Anti-Mouse SLC25A14 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1440-Ab-1/ GM-Tg-cynog-SE1440-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC25A14 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1440-Ab-1/ GM-Tg-felg-SE1440-Ab-2 | Anti-Feline SLC25A14 monoclonal antibody | Feline |
| GM-Tg-cang-SE1440-Ab-1/ GM-Tg-cang-SE1440-Ab-2 | Anti-Canine SLC25A14 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1440-Ab-1/ GM-Tg-bovg-SE1440-Ab-2 | Anti-Bovine SLC25A14 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1440-Ab-1/ GM-Tg-equg-SE1440-Ab-2 | Anti-Equine SLC25A14 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1440-Ab-1/ GM-Tg-hg-SE1440-Ab-2; GM-Tg-rg-SE1440-Ab-1/ GM-Tg-rg-SE1440-Ab-2; GM-Tg-mg-SE1440-Ab-1/ GM-Tg-mg-SE1440-Ab-2; GM-Tg-cynog-SE1440-Ab-1/ GM-Tg-cynog-SE1440-Ab-2; GM-Tg-felg-SE1440-Ab-1/ GM-Tg-felg-SE1440-Ab-2; GM-Tg-cang-SE1440-Ab-1/ GM-Tg-cang-SE1440-Ab-2; GM-Tg-bovg-SE1440-Ab-1/ GM-Tg-bovg-SE1440-Ab-2; GM-Tg-equg-SE1440-Ab-1/ GM-Tg-equg-SE1440-Ab-2 |
| Products Name | Anti-SLC25A14 monoclonal antibody |
| Format | mab |
| Target Name | SLC25A14 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC25A14 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1440-Ag-1 | Recombinant multi-species UCP5/ SLC25A14/ BMCP1 protein |
| ORF Viral Vector | vGMLP003260 | human SLC25A14 Lentivirus particle |
| ORF Viral Vector | pGMLP003260 | human SLC25A14 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001473 | mouse Slc25a14 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002133 | mouse Slc25a14 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001473 | mouse Slc25a14 Lentivirus particle |
| ORF Viral Vector | vGMLPm002133 | mouse Slc25a14 Lentivirus particle |
Target information
| Target ID | GM-SE1440 |
| Target Name | SLC25A14 |
| Gene ID | 9016,20523,85263,703255,612910,101082985,513415,100054503 |
| Gene Symbol and Synonyms | BMCP-1,BMCP1,SLC25A14,UCP5,UCP5L,UCP5S |
| Uniprot Accession | O95258 |
| Uniprot Entry Name | UCP5_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000102078 |
| Target Classification | N/A |
The target: SLC25A14, gene name: SLC25A14, also named as BMCP1, UCP5. Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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