Anti-DIAC/ CTBS/ CTB functional antibody

Anti-DIAC/ CTBS/ CTB functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CTBS/CTBS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1470-Ab-1/ GM-Tg-hg-SE1470-Ab-2Anti-Human CTBS monoclonal antibodyHuman
GM-Tg-rg-SE1470-Ab-1/ GM-Tg-rg-SE1470-Ab-2Anti-Rat CTBS monoclonal antibodyRat
GM-Tg-mg-SE1470-Ab-1/ GM-Tg-mg-SE1470-Ab-2Anti-Mouse CTBS monoclonal antibodyMouse
GM-Tg-cynog-SE1470-Ab-1/ GM-Tg-cynog-SE1470-Ab-2Anti-Cynomolgus/ Rhesus macaque CTBS monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1470-Ab-1/ GM-Tg-felg-SE1470-Ab-2Anti-Feline CTBS monoclonal antibodyFeline
GM-Tg-cang-SE1470-Ab-1/ GM-Tg-cang-SE1470-Ab-2Anti-Canine CTBS monoclonal antibodyCanine
GM-Tg-bovg-SE1470-Ab-1/ GM-Tg-bovg-SE1470-Ab-2Anti-Bovine CTBS monoclonal antibodyBovine
GM-Tg-equg-SE1470-Ab-1/ GM-Tg-equg-SE1470-Ab-2Anti-Equine CTBS monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1470-Ab-1/ GM-Tg-hg-SE1470-Ab-2; GM-Tg-rg-SE1470-Ab-1/ GM-Tg-rg-SE1470-Ab-2;
GM-Tg-mg-SE1470-Ab-1/ GM-Tg-mg-SE1470-Ab-2; GM-Tg-cynog-SE1470-Ab-1/ GM-Tg-cynog-SE1470-Ab-2;
GM-Tg-felg-SE1470-Ab-1/ GM-Tg-felg-SE1470-Ab-2; GM-Tg-cang-SE1470-Ab-1/ GM-Tg-cang-SE1470-Ab-2;
GM-Tg-bovg-SE1470-Ab-1/ GM-Tg-bovg-SE1470-Ab-2; GM-Tg-equg-SE1470-Ab-1/ GM-Tg-equg-SE1470-Ab-2
Products NameAnti-CTBS monoclonal antibody
Formatmab
Target NameCTBS
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CTBS benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1470-Ag-1Recombinant multi-species DIAC/ CTBS/ CTB protein
    ORF Viral VectorvGMLP001382human CTBS Lentivirus particle
    ORF Viral VectorpGMLP001382human CTBS Lentivirus plasmid
    ORF Viral VectorpGMLPm001845mouse Ctbs Lentivirus plasmid
    ORF Viral VectorvGMLPm001845mouse Ctbs Lentivirus particle


    Target information

    Target IDGM-SE1470
    Target NameCTBS
    Gene ID1486,74245,81652,710366,490188,109502427,524503,100064763
    Gene Symbol and Synonyms2210401K11Rik,CTB,CTBS
    Uniprot AccessionQ01459,Q01460,Q01458
    Uniprot Entry NameDIAC_HUMAN,DIAC_RAT,DIAC_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000117151
    Target ClassificationN/A

    The target: CTBS, gene name: CTBS, also named as CTB. Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.