Anti-DIAC/ CTBS/ CTB functional antibody
Anti-DIAC/ CTBS/ CTB functional antibody for cell culture, ELISA & in-vivo assay
Go to CTBS/CTBS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE1470-Ab-1/ GM-Tg-hg-SE1470-Ab-2 | Anti-Human CTBS monoclonal antibody | Human |
GM-Tg-rg-SE1470-Ab-1/ GM-Tg-rg-SE1470-Ab-2 | Anti-Rat CTBS monoclonal antibody | Rat |
GM-Tg-mg-SE1470-Ab-1/ GM-Tg-mg-SE1470-Ab-2 | Anti-Mouse CTBS monoclonal antibody | Mouse |
GM-Tg-cynog-SE1470-Ab-1/ GM-Tg-cynog-SE1470-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CTBS monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE1470-Ab-1/ GM-Tg-felg-SE1470-Ab-2 | Anti-Feline CTBS monoclonal antibody | Feline |
GM-Tg-cang-SE1470-Ab-1/ GM-Tg-cang-SE1470-Ab-2 | Anti-Canine CTBS monoclonal antibody | Canine |
GM-Tg-bovg-SE1470-Ab-1/ GM-Tg-bovg-SE1470-Ab-2 | Anti-Bovine CTBS monoclonal antibody | Bovine |
GM-Tg-equg-SE1470-Ab-1/ GM-Tg-equg-SE1470-Ab-2 | Anti-Equine CTBS monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE1470-Ab-1/ GM-Tg-hg-SE1470-Ab-2; GM-Tg-rg-SE1470-Ab-1/ GM-Tg-rg-SE1470-Ab-2; GM-Tg-mg-SE1470-Ab-1/ GM-Tg-mg-SE1470-Ab-2; GM-Tg-cynog-SE1470-Ab-1/ GM-Tg-cynog-SE1470-Ab-2; GM-Tg-felg-SE1470-Ab-1/ GM-Tg-felg-SE1470-Ab-2; GM-Tg-cang-SE1470-Ab-1/ GM-Tg-cang-SE1470-Ab-2; GM-Tg-bovg-SE1470-Ab-1/ GM-Tg-bovg-SE1470-Ab-2; GM-Tg-equg-SE1470-Ab-1/ GM-Tg-equg-SE1470-Ab-2 |
Products Name | Anti-CTBS monoclonal antibody |
Format | mab |
Target Name | CTBS |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CTBS benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE1470-Ag-1 | Recombinant multi-species DIAC/ CTBS/ CTB protein |
ORF Viral Vector | vGMLP001382 | human CTBS Lentivirus particle |
ORF Viral Vector | pGMLP001382 | human CTBS Lentivirus plasmid |
ORF Viral Vector | pGMLPm001845 | mouse Ctbs Lentivirus plasmid |
ORF Viral Vector | vGMLPm001845 | mouse Ctbs Lentivirus particle |
Target information
Target ID | GM-SE1470 |
Target Name | CTBS |
Gene ID | 1486,74245,81652,710366,490188,109502427,524503,100064763 |
Gene Symbol and Synonyms | 2210401K11Rik,CTB,CTBS |
Uniprot Accession | Q01459,Q01460,Q01458 |
Uniprot Entry Name | DIAC_HUMAN,DIAC_RAT,DIAC_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000117151 |
Target Classification | N/A |
The target: CTBS, gene name: CTBS, also named as CTB. Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.