Anti-KAD4/ AK4/ AK 4 functional antibody for cell culture, ELISA & in-vivo assay| GMab

Pre-made anti-AK4 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-AK4 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: AK4, gene name: AK4, also named as AK 4, AK3, AK3L1, AK3L2. This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008].

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Catalog No.	List Price (In USD)	Discount Price (In USD)	Qty (Quantity)	Sum (In USD)
GM-Tg-hg-SE1556-Ab-1-1mg	5150	3090
GM-Tg-hg-SE1556-Ab-1-10mg	Inquiry	Inquiry
GM-Tg-hg-SE1556-Ab-1-100mg	Inquiry	Inquiry
GM-Tg-hg-SE1556-Ab-2-1mg	5150	3090
GM-Tg-hg-SE1556-Ab-2-10mg	Inquiry	Inquiry
GM-Tg-hg-SE1556-Ab-2-100mg	Inquiry	Inquiry
GM-Tg-hg-SE1556-Ab-xmg	Inquiry	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Catalog No.	GM-Tg-hg-SE1556-Ab-1, GM-Tg-hg-SE1556-Ab-2
Products Name	Anti-AK4 monoclonal antibody
Format	mab
Target Name	AK4
Gene ID	AK4
Gene Name	AK4
Gene Alias	AK 4, AK3, AK3L1, AK3L2
Protein Sub-location	Secreted Protein/Potential Cytokines
Category of antibody	FACS/Biofunctional Antibody
Derivation (species)	Mouse
Species Reactivity	Human(H)
CH1+2+3 Isotype (Receptor identification)	IgG
Type of Light Chain (VD-LC)	N/A
Expression platform	Mammalian Expression
Bioactivity validation	Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Tag	Fc
Products description	Pre-made anti-AK4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity	Purity: ≥95% (SDS-PAGE)
Application	Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.