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Anti-PGLT1/ POGLUT1/ C3orf9 functional antibody
Anti-PGLT1/ POGLUT1/ C3orf9 functional antibody for cell culture, ELISA & in-vivo assay
Go to POGLUT1/POGLUT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1561-Ab-1/ GM-Tg-hg-SE1561-Ab-2 | Anti-Human POGLUT1 monoclonal antibody | Human |
| GM-Tg-rg-SE1561-Ab-1/ GM-Tg-rg-SE1561-Ab-2 | Anti-Rat POGLUT1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1561-Ab-1/ GM-Tg-mg-SE1561-Ab-2 | Anti-Mouse POGLUT1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1561-Ab-1/ GM-Tg-cynog-SE1561-Ab-2 | Anti-Cynomolgus/ Rhesus macaque POGLUT1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1561-Ab-1/ GM-Tg-felg-SE1561-Ab-2 | Anti-Feline POGLUT1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1561-Ab-1/ GM-Tg-cang-SE1561-Ab-2 | Anti-Canine POGLUT1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1561-Ab-1/ GM-Tg-bovg-SE1561-Ab-2 | Anti-Bovine POGLUT1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1561-Ab-1/ GM-Tg-equg-SE1561-Ab-2 | Anti-Equine POGLUT1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1561-Ab-1/ GM-Tg-hg-SE1561-Ab-2; GM-Tg-rg-SE1561-Ab-1/ GM-Tg-rg-SE1561-Ab-2; GM-Tg-mg-SE1561-Ab-1/ GM-Tg-mg-SE1561-Ab-2; GM-Tg-cynog-SE1561-Ab-1/ GM-Tg-cynog-SE1561-Ab-2; GM-Tg-felg-SE1561-Ab-1/ GM-Tg-felg-SE1561-Ab-2; GM-Tg-cang-SE1561-Ab-1/ GM-Tg-cang-SE1561-Ab-2; GM-Tg-bovg-SE1561-Ab-1/ GM-Tg-bovg-SE1561-Ab-2; GM-Tg-equg-SE1561-Ab-1/ GM-Tg-equg-SE1561-Ab-2 |
| Products Name | Anti-POGLUT1 monoclonal antibody |
| Format | mab |
| Target Name | POGLUT1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-POGLUT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1561-Ag-1 | Recombinant multi-species PGLT1/ POGLUT1/ C3orf9 protein |
| ORF Viral Vector | pGMLP001717 | human POGLUT1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001717 | human POGLUT1 Lentivirus particle |
| ORF Viral Vector | pGMLPm004000 | mouse Poglut1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004000 | mouse Poglut1 Lentivirus particle |
Target information
| Target ID | GM-SE1561 |
| Target Name | POGLUT1 |
| Gene ID | 56983,224143,288091,712357,487993,101088101,511862,100071030 |
| Gene Symbol and Synonyms | 9630046K23Rik,C3orf9,CLP46,hCLP46,KDELCL1,KTELC1,LGMD2Z,LGMDR21,MDS010,MDSRP,POGLUT1,RGD1306248,Rumi,wsnp |
| Uniprot Accession | Q8NBL1,G3V9D0,Q5E9Q1 |
| Uniprot Entry Name | PGLT1_HUMAN,PGLT1_RAT,PGLT1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000163389 |
| Target Classification | N/A |
The target: POGLUT1, gene name: POGLUT1, also named as C3orf9, CLP46, KDELCL1, KTELC1, LGMD2Z, LGMDR21, MDS010, MDSRP, Rumi, hCLP46. This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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