Anti-MYL1/ MLC1F/ MLC3F functional antibody

Anti-MYL1/ MLC1F/ MLC3F functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to MYL1/MYL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1588-Ab-1/ GM-Tg-hg-SE1588-Ab-2Anti-Human MYL1 monoclonal antibodyHuman
GM-Tg-rg-SE1588-Ab-1/ GM-Tg-rg-SE1588-Ab-2Anti-Rat MYL1 monoclonal antibodyRat
GM-Tg-mg-SE1588-Ab-1/ GM-Tg-mg-SE1588-Ab-2Anti-Mouse MYL1 monoclonal antibodyMouse
GM-Tg-cynog-SE1588-Ab-1/ GM-Tg-cynog-SE1588-Ab-2Anti-Cynomolgus/ Rhesus macaque MYL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1588-Ab-1/ GM-Tg-felg-SE1588-Ab-2Anti-Feline MYL1 monoclonal antibodyFeline
GM-Tg-cang-SE1588-Ab-1/ GM-Tg-cang-SE1588-Ab-2Anti-Canine MYL1 monoclonal antibodyCanine
GM-Tg-bovg-SE1588-Ab-1/ GM-Tg-bovg-SE1588-Ab-2Anti-Bovine MYL1 monoclonal antibodyBovine
GM-Tg-equg-SE1588-Ab-1/ GM-Tg-equg-SE1588-Ab-2Anti-Equine MYL1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1588-Ab-1/ GM-Tg-hg-SE1588-Ab-2; GM-Tg-rg-SE1588-Ab-1/ GM-Tg-rg-SE1588-Ab-2;
GM-Tg-mg-SE1588-Ab-1/ GM-Tg-mg-SE1588-Ab-2; GM-Tg-cynog-SE1588-Ab-1/ GM-Tg-cynog-SE1588-Ab-2;
GM-Tg-felg-SE1588-Ab-1/ GM-Tg-felg-SE1588-Ab-2; GM-Tg-cang-SE1588-Ab-1/ GM-Tg-cang-SE1588-Ab-2;
GM-Tg-bovg-SE1588-Ab-1/ GM-Tg-bovg-SE1588-Ab-2; GM-Tg-equg-SE1588-Ab-1/ GM-Tg-equg-SE1588-Ab-2
Products NameAnti-MYL1 monoclonal antibody
Formatmab
Target NameMYL1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MYL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1588-Ag-1Recombinant multi-species MYL1/ MLC1F/ MLC3F protein
    ORF Viral VectorpGMLP000342human MYL1 Lentivirus plasmid
    ORF Viral VectorvGMLP000342human MYL1 Lentivirus particle


    Target information

    Target IDGM-SE1588
    Target NameMYL1
    Gene ID4632,17901,56781,711561,478896,101099140,317657,100052501
    Gene Symbol and SynonymsCMYP14,Mcl3,MLC-1,MLC-f,MLC1,MLC1/3,MLC1F,Mlc3,MLC3-f,MLC3F,MLCf,MYL1,Mylf,MYOFTA
    Uniprot AccessionP05976,P02600,A0JNJ5
    Uniprot Entry NameMYL1_HUMAN,MYL1_RAT,MYL1_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168530
    Target ClassificationN/A

    The target: MYL1, gene name: MYL1, also named as MLC1F, MLC3F. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.