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Anti-SELM/ SELENOM/ SEPM functional antibody
Anti-SELM/ SELENOM/ SEPM functional antibody for cell culture, ELISA & in-vivo assay
Go to SELENOM/SELENOM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1651-Ab-1/ GM-Tg-hg-SE1651-Ab-2 | Anti-Human SELENOM monoclonal antibody | Human |
| GM-Tg-rg-SE1651-Ab-1/ GM-Tg-rg-SE1651-Ab-2 | Anti-Rat SELENOM monoclonal antibody | Rat |
| GM-Tg-mg-SE1651-Ab-1/ GM-Tg-mg-SE1651-Ab-2 | Anti-Mouse SELENOM monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1651-Ab-1/ GM-Tg-cynog-SE1651-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SELENOM monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1651-Ab-1/ GM-Tg-felg-SE1651-Ab-2 | Anti-Feline SELENOM monoclonal antibody | Feline |
| GM-Tg-cang-SE1651-Ab-1/ GM-Tg-cang-SE1651-Ab-2 | Anti-Canine SELENOM monoclonal antibody | Canine |
| GM-Tg-bovg-SE1651-Ab-1/ GM-Tg-bovg-SE1651-Ab-2 | Anti-Bovine SELENOM monoclonal antibody | Bovine |
| GM-Tg-equg-SE1651-Ab-1/ GM-Tg-equg-SE1651-Ab-2 | Anti-Equine SELENOM monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1651-Ab-1/ GM-Tg-hg-SE1651-Ab-2; GM-Tg-rg-SE1651-Ab-1/ GM-Tg-rg-SE1651-Ab-2; GM-Tg-mg-SE1651-Ab-1/ GM-Tg-mg-SE1651-Ab-2; GM-Tg-cynog-SE1651-Ab-1/ GM-Tg-cynog-SE1651-Ab-2; GM-Tg-felg-SE1651-Ab-1/ GM-Tg-felg-SE1651-Ab-2; GM-Tg-cang-SE1651-Ab-1/ GM-Tg-cang-SE1651-Ab-2; GM-Tg-bovg-SE1651-Ab-1/ GM-Tg-bovg-SE1651-Ab-2; GM-Tg-equg-SE1651-Ab-1/ GM-Tg-equg-SE1651-Ab-2 |
| Products Name | Anti-SELENOM monoclonal antibody |
| Format | mab |
| Target Name | SELENOM |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SELENOM benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1651-Ag-1 | Recombinant multi-species SELM/ SELENOM/ SEPM protein |
| ORF Viral Vector | pGMLP000002 | human SELENOM Lentivirus plasmid |
| ORF Viral Vector | vGMLP002806 | human SELENOM Lentivirus particle |
| ORF Viral Vector | pGMAD000365 | human SELENOM Adenovirus plasmid |
| ORF Viral Vector | pGMLP002806 | human SELENOM Lentivirus plasmid |
| ORF Viral Vector | vGMAD000365 | human SELENOM Adenovirus particle |
| ORF Viral Vector | vGMLP000002 | human SELENOM Lentivirus particle |
| ORF Viral Vector | pGMLPm000640 | mouse Selenom Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000640 | mouse Selenom Lentivirus particle |
Target information
| Target ID | GM-SE1651 |
| Target Name | SELENOM |
| Gene ID | 140606,114679,498398,718290,611981,101095443,787736,100063305 |
| Gene Symbol and Synonyms | 1500040L08Rik,A230103K18,RGD1565037,SELENOM,SELM,SEPM |
| Uniprot Accession | Q8WWX9 |
| Uniprot Entry Name | SELM_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000198832 |
| Target Classification | N/A |
The target: SELENOM, gene name: SELENOM, also named as SELM, SEPM. The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Dec 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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