Anti-PRCD/ RP36 functional antibody

Anti-PRCD/ RP36 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PRCD/PRCD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1657-Ab-1/ GM-Tg-hg-SE1657-Ab-2Anti-Human PRCD monoclonal antibodyHuman
GM-Tg-rg-SE1657-Ab-1/ GM-Tg-rg-SE1657-Ab-2Anti-Rat PRCD monoclonal antibodyRat
GM-Tg-mg-SE1657-Ab-1/ GM-Tg-mg-SE1657-Ab-2Anti-Mouse PRCD monoclonal antibodyMouse
GM-Tg-cynog-SE1657-Ab-1/ GM-Tg-cynog-SE1657-Ab-2Anti-Cynomolgus/ Rhesus macaque PRCD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1657-Ab-1/ GM-Tg-felg-SE1657-Ab-2Anti-Feline PRCD monoclonal antibodyFeline
GM-Tg-cang-SE1657-Ab-1/ GM-Tg-cang-SE1657-Ab-2Anti-Canine PRCD monoclonal antibodyCanine
GM-Tg-bovg-SE1657-Ab-1/ GM-Tg-bovg-SE1657-Ab-2Anti-Bovine PRCD monoclonal antibodyBovine
GM-Tg-equg-SE1657-Ab-1/ GM-Tg-equg-SE1657-Ab-2Anti-Equine PRCD monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1657-Ab-1/ GM-Tg-hg-SE1657-Ab-2; GM-Tg-rg-SE1657-Ab-1/ GM-Tg-rg-SE1657-Ab-2;
GM-Tg-mg-SE1657-Ab-1/ GM-Tg-mg-SE1657-Ab-2; GM-Tg-cynog-SE1657-Ab-1/ GM-Tg-cynog-SE1657-Ab-2;
GM-Tg-felg-SE1657-Ab-1/ GM-Tg-felg-SE1657-Ab-2; GM-Tg-cang-SE1657-Ab-1/ GM-Tg-cang-SE1657-Ab-2;
GM-Tg-bovg-SE1657-Ab-1/ GM-Tg-bovg-SE1657-Ab-2; GM-Tg-equg-SE1657-Ab-1/ GM-Tg-equg-SE1657-Ab-2
Products NameAnti-PRCD monoclonal antibody
Formatmab
Target NamePRCD
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRCD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1657-Ag-1Recombinant multi-species PRCD/ RP36 protein
    ORF Viral VectorvGMLP001835human PRCD Lentivirus particle
    ORF Viral VectorpGMLP001835human PRCD Lentivirus plasmid
    ORF Viral VectorpGMLPm000870mouse Prcd Lentivirus plasmid
    ORF Viral VectorvGMLPm000870mouse Prcd Lentivirus particle


    Target information

    Target IDGM-SE1657
    Target NamePRCD
    Gene ID768206,100038570,100912216,106994137,100049006,101085163,100051104
    Gene Symbol and SynonymsGm11744,PRCD,RP36
    Uniprot AccessionQ00LT1,Q00LT9
    Uniprot Entry NamePRCD_HUMAN,PRCD_CANLF
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000214140
    Target ClassificationN/A

    The target: PRCD, gene name: PRCD, also named as RP36. This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.