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Anti-PRCD/ RP36 functional antibody
Anti-PRCD/ RP36 functional antibody for cell culture, ELISA & in-vivo assay
Go to PRCD/PRCD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1657-Ab-1/ GM-Tg-hg-SE1657-Ab-2 | Anti-Human PRCD monoclonal antibody | Human |
| GM-Tg-rg-SE1657-Ab-1/ GM-Tg-rg-SE1657-Ab-2 | Anti-Rat PRCD monoclonal antibody | Rat |
| GM-Tg-mg-SE1657-Ab-1/ GM-Tg-mg-SE1657-Ab-2 | Anti-Mouse PRCD monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1657-Ab-1/ GM-Tg-cynog-SE1657-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRCD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1657-Ab-1/ GM-Tg-felg-SE1657-Ab-2 | Anti-Feline PRCD monoclonal antibody | Feline |
| GM-Tg-cang-SE1657-Ab-1/ GM-Tg-cang-SE1657-Ab-2 | Anti-Canine PRCD monoclonal antibody | Canine |
| GM-Tg-bovg-SE1657-Ab-1/ GM-Tg-bovg-SE1657-Ab-2 | Anti-Bovine PRCD monoclonal antibody | Bovine |
| GM-Tg-equg-SE1657-Ab-1/ GM-Tg-equg-SE1657-Ab-2 | Anti-Equine PRCD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1657-Ab-1/ GM-Tg-hg-SE1657-Ab-2; GM-Tg-rg-SE1657-Ab-1/ GM-Tg-rg-SE1657-Ab-2; GM-Tg-mg-SE1657-Ab-1/ GM-Tg-mg-SE1657-Ab-2; GM-Tg-cynog-SE1657-Ab-1/ GM-Tg-cynog-SE1657-Ab-2; GM-Tg-felg-SE1657-Ab-1/ GM-Tg-felg-SE1657-Ab-2; GM-Tg-cang-SE1657-Ab-1/ GM-Tg-cang-SE1657-Ab-2; GM-Tg-bovg-SE1657-Ab-1/ GM-Tg-bovg-SE1657-Ab-2; GM-Tg-equg-SE1657-Ab-1/ GM-Tg-equg-SE1657-Ab-2 |
| Products Name | Anti-PRCD monoclonal antibody |
| Format | mab |
| Target Name | PRCD |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRCD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1657-Ag-1 | Recombinant multi-species PRCD/ RP36 protein |
| ORF Viral Vector | vGMLP001835 | human PRCD Lentivirus particle |
| ORF Viral Vector | pGMLP001835 | human PRCD Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000870 | mouse Prcd Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000870 | mouse Prcd Lentivirus particle |
Target information
| Target ID | GM-SE1657 |
| Target Name | PRCD |
| Gene ID | 768206,100038570,100912216,106994137,100049006,101085163,100051104 |
| Gene Symbol and Synonyms | Gm11744,PRCD,RP36 |
| Uniprot Accession | Q00LT1,Q00LT9 |
| Uniprot Entry Name | PRCD_HUMAN,PRCD_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000214140 |
| Target Classification | N/A |
The target: PRCD, gene name: PRCD, also named as RP36. This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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