Anti-CL3L1/ CCL3L1/ D17S1718 functional antibody
Anti-CL3L1/ CCL3L1/ D17S1718 functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE1673-Ab-1/ GM-Tg-hg-SE1673-Ab-2 | Anti-Human CCL3L1 monoclonal antibody | Human |
GM-Tg-rg-SE1673-Ab-1/ GM-Tg-rg-SE1673-Ab-2 | Anti-Rat CCL3L1 monoclonal antibody | Rat |
GM-Tg-mg-SE1673-Ab-1/ GM-Tg-mg-SE1673-Ab-2 | Anti-Mouse CCL3L1 monoclonal antibody | Mouse |
GM-Tg-cynog-SE1673-Ab-1/ GM-Tg-cynog-SE1673-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL3L1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE1673-Ab-1/ GM-Tg-felg-SE1673-Ab-2 | Anti-Feline CCL3L1 monoclonal antibody | Feline |
GM-Tg-cang-SE1673-Ab-1/ GM-Tg-cang-SE1673-Ab-2 | Anti-Canine CCL3L1 monoclonal antibody | Canine |
GM-Tg-bovg-SE1673-Ab-1/ GM-Tg-bovg-SE1673-Ab-2 | Anti-Bovine CCL3L1 monoclonal antibody | Bovine |
GM-Tg-equg-SE1673-Ab-1/ GM-Tg-equg-SE1673-Ab-2 | Anti-Equine CCL3L1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE1673-Ab-1/ GM-Tg-hg-SE1673-Ab-2; GM-Tg-rg-SE1673-Ab-1/ GM-Tg-rg-SE1673-Ab-2; GM-Tg-mg-SE1673-Ab-1/ GM-Tg-mg-SE1673-Ab-2; GM-Tg-cynog-SE1673-Ab-1/ GM-Tg-cynog-SE1673-Ab-2; GM-Tg-felg-SE1673-Ab-1/ GM-Tg-felg-SE1673-Ab-2; GM-Tg-cang-SE1673-Ab-1/ GM-Tg-cang-SE1673-Ab-2; GM-Tg-bovg-SE1673-Ab-1/ GM-Tg-bovg-SE1673-Ab-2; GM-Tg-equg-SE1673-Ab-1/ GM-Tg-equg-SE1673-Ab-2 |
Products Name | Anti-CCL3L1 monoclonal antibody |
Format | mab |
Target Name | CCL3L1 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CCL3L1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE1673-Ag-1 | Recombinant multi-species CL3L1/ CCL3L1/ D17S1718 protein |
ORF Viral Vector | pGMLP000966 | human CCL3L1 Lentivirus plasmid |
ORF Viral Vector | vGMLP000966 | human CCL3L1 Lentivirus particle |
Target information
Target ID | GM-SE1673 |
Target Name | CCL3L1 |
Gene ID | 6349 |
Gene Symbol and Synonyms | 464.2,CCL3L1,D17S1718,G0S19-2,LD78,LD78-beta(1-70),LD78BETA,MIP1AP,SCYA3L,SCYA3L1 |
Uniprot Accession | P16619 |
Uniprot Entry Name | CL3L1_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000277796 |
Target Classification | N/A |
The target: CCL3L1, gene name: CCL3L1, also named as 464.2, D17S1718, G0S19-2, LD78, LD78-beta(1-70), LD78BETA, MIP1AP, SCYA3L, SCYA3L1. This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.