Anti-5HT1F/ HTR1F/ 5-HT-1F monoclonal antibody

Anti-5HT1F/ HTR1F/ 5-HT-1F antibody for FACS & in-vivo assay

Target products collectionGo to HTR1F/HTR1F products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T78656-Ab-1/ GM-Tg-hg-T78656-Ab-2Anti-Human HTR1F monoclonal antibodyHuman
GM-Tg-rg-T78656-Ab-1/ GM-Tg-rg-T78656-Ab-2Anti-Rat HTR1F monoclonal antibodyRat
GM-Tg-mg-T78656-Ab-1/ GM-Tg-mg-T78656-Ab-2Anti-Mouse HTR1F monoclonal antibodyMouse
GM-Tg-cynog-T78656-Ab-1/ GM-Tg-cynog-T78656-Ab-2Anti-Cynomolgus/ Rhesus macaque HTR1F monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T78656-Ab-1/ GM-Tg-felg-T78656-Ab-2Anti-Feline HTR1F monoclonal antibodyFeline
GM-Tg-cang-T78656-Ab-1/ GM-Tg-cang-T78656-Ab-2Anti-Canine HTR1F monoclonal antibodyCanine
GM-Tg-bovg-T78656-Ab-1/ GM-Tg-bovg-T78656-Ab-2Anti-Bovine HTR1F monoclonal antibodyBovine
GM-Tg-equg-T78656-Ab-1/ GM-Tg-equg-T78656-Ab-2Anti-Equine HTR1F monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T78656-Ab-1/ GM-Tg-hg-T78656-Ab-2; GM-Tg-rg-T78656-Ab-1/ GM-Tg-rg-T78656-Ab-2;
GM-Tg-mg-T78656-Ab-1/ GM-Tg-mg-T78656-Ab-2; GM-Tg-cynog-T78656-Ab-1/ GM-Tg-cynog-T78656-Ab-2;
GM-Tg-felg-T78656-Ab-1/ GM-Tg-felg-T78656-Ab-2; GM-Tg-cang-T78656-Ab-1/ GM-Tg-cang-T78656-Ab-2;
GM-Tg-bovg-T78656-Ab-1/ GM-Tg-bovg-T78656-Ab-2; GM-Tg-equg-T78656-Ab-1/ GM-Tg-equg-T78656-Ab-2
Products NameAnti-HTR1F monoclonal antibody
Formatmab
Target NameHTR1F
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-HTR1F benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species 5HT1F/ HTR1F/ 5-HT-1F VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T78656
    Target NameHTR1F
    Gene ID3355,15557,60448,693418,100683938,101100323,407196,100054385
    Gene Symbol and Synonyms5-HT-1F,5-HT1F,5HT6,5htr1e,5htr1f,Htr1eb,HTR1EL,HTR1F,MR77
    Uniprot AccessionP30939,P30940
    Uniprot Entry Name5HT1F_HUMAN,5HT1F_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000179097
    Target ClassificationGPCR

    The target: HTR1F, gene name: HTR1F, also named as 5-HT-1F, 5-HT1F, 5HT6, HTR1EL, MR77. Enables G protein-coupled serotonin receptor activity and serotonin binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.