Canine BNP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-BNP-Ag01	Recombinant Canine BNP protein	3090
GMP-CAN-BNP-Ab01	Anti-Canine BNP mouse monoclonal antibody (mAb)	1953
GMP-CAN-BNP-Ab02	Anti-Canine BNP mouse monoclonal antibody (mAb)	1953
GMP-CAN-BNP-Ab03	Anti-Canine BNP human monoclonal antibody (mAb)	1953
GMP-CAN-BNP-Ab04	Anti-Canine BNP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-BNP-Ag01
Product Name	Recombinant Canine BNP protein
Target/Biomarker	Duck Enteritis Virus/Anatid Herpesvirus 1 (DEV)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Duck Enteritis Virus/Anatid Herpesvirus 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in DEV level test of animal Dog/Canine with Cardiovascular Disease.
Tag	His
Products description	Recombinant Canine BNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-BNP-Ab01, GMP-CAN-BNP-Ab02
Product Name	Anti-Canine BNP mouse monoclonal antibody (mAb)
Target/Biomarker	Duck Enteritis Virus/Anatid Herpesvirus 1 (DEV)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Duck Enteritis Virus/Anatid Herpesvirus 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-DEV antibodies in DEV level test of animal Dog/Canine with Cardiovascular Disease.
Tag	mFc
Products description	Anti-Canine BNP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-DEV antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-BNP-Ab03, GMP-CAN-BNP-Ab04
Product Name	Anti-Canine BNP human monoclonal antibody (mAb)
Target/Biomarker	Duck Enteritis Virus/Anatid Herpesvirus 1 (DEV)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Duck Enteritis Virus/Anatid Herpesvirus 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-DEV antibodies in DEV level test of animal Dog/Canine with Cardiovascular Disease.
Tag	hFc
Products description	Anti-Canine BNP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-DEV antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine B-type Natriuretic Peptide, or Canine BNP, stands as a remarkable biomarker in the intricate orchestra of canine cardiovascular health. Synthesized primarily within the ventricles of the heart in domestic dogs (Canis lupus familiaris), BNP is a member of the natriuretic peptide family, joining forces with atrial natriuretic peptide (ANP) to orchestrate blood pressure and fluid balance in the canine body. The production and release of Canine BNP are intricately regulated processes. When the heart faces increased pressure or volume overload, often resulting from conditions like congestive heart failure (CHF), valvular disease, or cardiomyopathy, the ventricles respond by liberating BNP into the bloodstream. This natural response aims to mitigate the strain on the heart and enhance cardiovascular stability. Canine BNP, upon release, initiates a chain of events by binding to specific receptors in the kidneys and blood vessels. This binding event triggers a cascade that culminates in increased sodium and water excretion by the kidneys. By promoting diuresis, BNP contributes to the reduction of blood volume and a decrease in cardiac workload. The significance of Canine BNP goes beyond its role as a simple hormonal regulator. It serves as a sentinel, a messenger that heralds changes within the canine cardiovascular system. Elevated Canine BNP levels signal the presence of cardiac challenges, often before clinical symptoms manifest. As a result, Canine BNP is a powerful diagnostic tool, allowing veterinarians to detect heart-related issues early and intervene promptly.

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