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Canine HER2 antibody and antigen (recombinant protein)
Diagnostic anti-Canine HER2 antibodies pairs and antigen for animal health (animal Dog/Canine breast cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-HER2-Ag01 | Canine HER2 | $3090.00 |
| GMP-CAN-HER2-Ab01 | Anti-Canine HER2 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-HER2-Ab02 | Anti-Canine HER2 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-HER2-Ab03 | Anti-Canine HER2 human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-HER2-Ab04 | Anti-Canine HER2 human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-HER2-Ag01 |
| Product Name | Canine HER2 |
| Target/Biomarker | Canine HER2 |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine HER2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HER2 level test of animal Dog/Canine with breast cancer. |
| Tag | His | Reconized/Reactive Specics | Canine HER2 |
| Product description | Recombinant Canine HER2 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-HER2-Ab01,GMP-CAN-HER2-Ab02 |
| Target/Biomarker | Canine HER2 |
| Product Name | Anti-Canine HER2 mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine HER2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine HER2 antibodies in Canine HER2 level test of animal Dog/Canine with breast cancer. |
| Product description | Anti-Canine HER2 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine HER2 antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-HER2-Ab03,GMP-CAN-HER2-Ab04 |
| Target/Biomarker | Canine HER2 |
| Product Name | Anti-Canine HER2 human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine HER2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine HER2 antibodies in Canine HER2 level test of animal Dog/Canine with breast cancer. |
| Product description | Anti-Canine HER2 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
HER2, also known as Human Epidermal Growth Factor Receptor 2, is a biomarker of significant importance within the realm of dogs (canines). This transmembrane protein receptor belongs to the epidermal growth factor receptor (EGFR) family and is primarily found on the surface of certain canine cells. Its primary role is to regulate cell growth and proliferation by participating in intracellular signaling pathways that promote cell division.
In normal canine cells, HER2 plays a crucial role in maintaining a balanced and controlled rate of cell growth. It does so by facilitating the transmission of growth-promoting signals. However, when genetic mutations or alterations in HER2 expression occur, this finely tuned system can go awry, leading to uncontrolled cell growth—a hallmark feature of cancer. The significance of HER2 abnormalities becomes particularly pronounced in the context of canine mammary gland tumors, where HER2 overexpression is associated with aggressive tumor behavior.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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