Feline ApoE antibody and antigen (recombinant protein)

Diagnostic anti-Feline ApoE antibodies pairs and antigen for animal health (animal Cat/Feline Cardiovascular Disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-ApoE-Ag01Feline ApoE$3090.00
GMP-FEL-ApoE-Ab01Anti-Feline ApoE mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-ApoE-Ab02Anti-Feline ApoE mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-ApoE-Ab03Anti-Feline ApoE human monoclonal antibody (mAb)$3090.00
GMP-FEL-ApoE-Ab04Anti-Feline ApoE human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-ApoE-Ag01
Product NameFeline ApoE
Target/BiomarkerFeline ApoE
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline ApoE antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ApoE level test of animal Cat/Feline with Cardiovascular Disease.
TagHis
Reconized/Reactive SpecicsFeline ApoE
Product descriptionRecombinant Feline ApoE protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-ApoE-Ab01,GMP-FEL-ApoE-Ab02
Target/BiomarkerFeline ApoE
Product NameAnti-Feline ApoE mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline ApoE antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ApoE antibodies in Feline ApoE level test of animal Cat/Feline with Cardiovascular Disease.
Product descriptionAnti-Feline ApoE mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ApoE antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-ApoE-Ab03,GMP-FEL-ApoE-Ab04
Target/BiomarkerFeline ApoE
Product NameAnti-Feline ApoE human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline ApoE antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ApoE antibodies in Feline ApoE level test of animal Cat/Feline with Cardiovascular Disease.
Product descriptionAnti-Feline ApoE mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Apolipoprotein E, more commonly referred to as Feline ApoE, is a multifaceted protein that takes center stage in the intricate realm of feline physiology. Synthesized predominantly in the liver of domestic cats (Felis catus), this glycoprotein exhibits structural uniqueness due to the presence of carbohydrates attached to its polypeptide chain. As a distinguished member of the apolipoprotein family, Feline ApoE plays a pivotal role in regulating lipid metabolism, with a particular emphasis on cholesterol management within the feline body.

    The significance of Feline ApoE becomes most apparent in its association with high-density lipoproteins (HDL), widely recognized as "good cholesterol." HDL particles serve as molecular transporters for cholesterol and lipids in the bloodstream, and at the core of their functionality lies Feline ApoE. This biomarker is an indispensable component of HDLs, contributing not only to their structural integrity but also to their dynamic role in the reverse cholesterol transport pathway.

    The choreography of cholesterol transport begins when Feline ApoE binds to lipids, effectively transforming nascent HDL particles into active carriers of excess cholesterol. These HDLs venture into peripheral tissues, retrieving surplus cholesterol and lipids, and then embark on a journey back to the liver. In the liver, cholesterol undergoes metabolism and eventual excretion, thereby ensuring the maintenance of healthy cholesterol levels within the feline body.



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    GDU

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