Feline CYFRA21-1 antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-FEL-CYFRA21-1-Ag01	Recombinant Feline CYFRA21-1 protein	3090
GMP-FEL-CYFRA21-1-Ab01	Anti-Feline CYFRA21-1 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-CYFRA21-1-Ab02	Anti-Feline CYFRA21-1 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-CYFRA21-1-Ab03	Anti-Feline CYFRA21-1 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-CYFRA21-1-Ab04	Anti-Feline CYFRA21-1 mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-FEL-CYFRA21-1-Ag01
Product Name	Recombinant Feline CYFRA21-1 protein
Target/Biomarker	Feline soluble fragment of cytokeratin-19 (CYFRA21-1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline soluble fragment of cytokeratin-19 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CYFRA21-1 level test of animal Cat/Feline with bronchopulmonary dysplasia.
Tag	His
Products description	Recombinant Feline CYFRA21-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-CYFRA21-1-Ab01, GMP-FEL-CYFRA21-1-Ab02, GMP-FEL-CYFRA21-1-Ab03, GMP-FEL-CYFRA21-1-Ab04
Product Name	Anti-Feline CYFRA21-1 mouse monoclonal antibody (mAb)
Target/Biomarker	Feline soluble fragment of cytokeratin-19 (CYFRA21-1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Feline soluble fragment of cytokeratin-19 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CYFRA21-1 level test of animal Cat/Feline with bronchopulmonary dysplasia.
Tag	mFc
Products description	Anti-Feline CYFRA21-1 mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

CYFRA21-1, also known as Cytokeratin 19 Fragment 21-1, is a noteworthy biomarker within the context of cats (felines). It originates from cytokeratin 19, a structural protein that plays a pivotal role in maintaining the cytoskeletal integrity of epithelial cells. Epithelial cells are a fundamental component of various feline tissues and organs, including the respiratory system. When these cells experience pathological changes, such as injury or malignant transformation, CYFRA21-1 fragments can be released into the bloodstream, making it a valuable indicator of epithelial cell health. At the molecular level, CYFRA21-1 is composed of specific fragments of cytokeratin 19, notably the 21-1 fragment. These soluble protein fragments can be detected through blood tests. In healthy cats, CYFRA21-1 levels are typically low. However, when there is damage or malignancy in epithelial tissues, such as the lungs, the levels of CYFRA21-1 can significantly increase. This makes CYFRA21-1 a crucial biomarker for assessing the health of the respiratory and epithelial systems in felines.

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