Feline FIB antibody and antigen (recombinant protein)

Diagnostic anti-Feline FIB antibodies pairs and antigen for animal health (animal Cat/Feline congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-FIB-Ag01Feline FIB$3090.00
GMP-FEL-FIB-Ab01Anti-Feline FIB mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-FIB-Ab02Anti-Feline FIB mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-FIB-Ab03Anti-Feline FIB human monoclonal antibody (mAb)$3090.00
GMP-FEL-FIB-Ab04Anti-Feline FIB human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-FIB-Ag01
Product NameFeline FIB
Target/BiomarkerFeline FIB
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline FIB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FIB level test of animal Cat/Feline with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
TagHis
Reconized/Reactive SpecicsFeline FIB
Product descriptionRecombinant Feline FIB protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-FIB-Ab01,GMP-FEL-FIB-Ab02
Target/BiomarkerFeline FIB
Product NameAnti-Feline FIB mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline FIB antibodies in Feline FIB level test of animal Cat/Feline with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
Product descriptionAnti-Feline FIB mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline FIB antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-FIB-Ab03,GMP-FEL-FIB-Ab04
Target/BiomarkerFeline FIB
Product NameAnti-Feline FIB human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline FIB antibodies in Feline FIB level test of animal Cat/Feline with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
Product descriptionAnti-Feline FIB mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Fibrinogen, a remarkable component of the feline circulatory system, warrants a closer examination. Structurally, it is a glycoprotein of notable complexity, consisting of three intertwining polypeptide chains: alpha, beta, and gamma. These chains unite to form a large hexameric molecule with a molecular mass of approximately 340 kDa. The synthesis of Feline Fibrinogen predominantly occurs in the hepatocytes of the liver, after which it enters the bloodstream, poised for its crucial role in hemostasis.

    At the core of Feline Fibrinogen's function lies its conversion to fibrin, a process that serves as the linchpin of blood clot formation. In response to vascular injury or other hemostatic triggers, the enzyme thrombin catalyzes the cleavage of FIB's alpha and beta chains. This enzymatic reaction liberates fibrin, which undergoes rapid polymerization, creating long strands. These strands intertwine to form a meshwork, the scaffold of a blood clot that effectively halts bleeding.

    The dynamic nature of Feline Fibrinogen makes it a versatile and responsive biomarker. During episodes of inflammation, infection, or tissue injury, its synthesis escalates as part of the acute-phase response. This heightened production equips the body with an enhanced capacity to form blood clots at sites of injury, reinforcing the physiological defense mechanisms against potential threats.



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