Feline TPO antibody and antigen (recombinant protein)

Diagnostic anti-Feline TPO antibodies pairs and antigen for animal health (animal Cat/Feline Hashimoto's disease or Graves' disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-TPO-Ag01Feline TPO$3090.00
GMP-FEL-TPO-Ab01Anti-Feline TPO mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-TPO-Ab02Anti-Feline TPO mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-TPO-Ab03Anti-Feline TPO human monoclonal antibody (mAb)$3090.00
GMP-FEL-TPO-Ab04Anti-Feline TPO human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-TPO-Ag01
Product NameFeline TPO
Target/BiomarkerFeline TPO
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline TPO antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TPO level test of animal Cat/Feline with Hashimoto's disease or Graves' disease.
TagHis
Reconized/Reactive SpecicsFeline TPO
Product descriptionRecombinant Feline TPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-TPO-Ab01,GMP-FEL-TPO-Ab02
Target/BiomarkerFeline TPO
Product NameAnti-Feline TPO mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline TPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TPO antibodies in Feline TPO level test of animal Cat/Feline with Hashimoto's disease or Graves' disease.
Product descriptionAnti-Feline TPO mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TPO antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-TPO-Ab03,GMP-FEL-TPO-Ab04
Target/BiomarkerFeline TPO
Product NameAnti-Feline TPO human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline TPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TPO antibodies in Feline TPO level test of animal Cat/Feline with Hashimoto's disease or Graves' disease.
Product descriptionAnti-Feline TPO mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Thyroid Peroxidase (TPO) in cats (felines) emerges as a keystone biomarker that transcends its enzymatic role to become a linchpin of thyroid health, metabolic regulation, and overall well-being. Housed predominantly within the thyroid gland, TPO orchestrates a symphony of biochemical reactions essential to a cat's metabolic equilibrium.

    The defining function of TPO revolves around its enzymatic prowess, culminating in the catalysis of iodination. Specifically, TPO catalyzes the iodination of tyrosine residues residing on thyroglobulin, a substantial glycoprotein produced within the confines of thyroid follicular cells. This intricate molecular dance represents a pivotal step in the synthesis of thyroid hormones, including thyroxine (T4) and triiodothyronine (T3), which govern a myriad of physiological processes in cats.

    TPO's catalytic mastery unfolds through the incorporation of iodine atoms onto specific tyrosine residues within thyroglobulin. This chemical transformation begets iodinated tyrosines, which, in subsequent coupling reactions, give rise to the biologically active thyroid hormones T4 and T3. These hormones wield authoritative control over metabolic pathways, influencing energy utilization, thermoregulation, growth, and a spectrum of physiological systems within a cat's body.



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