Diagnostic recombinant pepsinogen I (PG I) antigens (recombinant pepsinogen I (PG I) ) protein) for gastric disease PG I detection in positive control, ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

There are two main types of pepsinogen (PG), namely PG I (PG A) and PG II (PG C). Both of these types are produced in the essential cells in the stomach corpus and fundus and in mucous cervical cells. Unlike PG A, PG C is also produced in the Brunner glands in the proximal duodenum and in the pyloric glands in the antrum [8]. Serum pepsinogen levels reflect the morphological and functional status of the stomach mucosa, so they serve as markers of chronic atrophic gastritis [9]. Low levels of serum PG A and PG A / PG C are observed in patients with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer [8]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261308/

Genemedi produces core diagnostic ingredients for test of gastric disease and related syndrome. GeneMedi offers paired diagnostics grade pepsinogen I (PG I) antibodies (monoclonal antibody, mab) and pepsinogen I (PG I) antigens for gastric disease rapid test kit of pepsinogen I (PG I) testing in positive control, ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

All the antibodies and antigens for gastric disease test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibodies can act as a capture antibody and detection antibody. The antigens can be used for antibodies rapid test of gastric disease.

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