Turkey Hepatitis Virus antibody and antigen (recombinant protein)

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Diagnostic anti-Turkey Hepatitis Virus antibodies pairs and antigen for animal health (animal Turkey infectious disease Turkey Hepatitis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P166-Tg001-Ag01	Recombinant Turkey Hepatitis Virus protein	$3090.00
GMP-VT-P166-Tg001-Ab01	Anti-Turkey Hepatitis Virus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P166-Tg001-Ab02	Anti-Turkey Hepatitis Virus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P166-Tg001-Ab03	Anti-Turkey Hepatitis Virus human monoclonal antibody (mAb)	$3090.00
GMP-VT-P166-Tg001-Ab04	Anti-Turkey Hepatitis Virus human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P166-Tg001-Ag01
Product Name	Recombinant Turkey Hepatitis Virus protein
Pathogen	Turkey Hepatitis Virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Turkey Hepatitis Virus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Turkey Hepatitis Virus level test of animal Turkey infectious disease with Turkey Hepatitis.
Tag	His
Product description	Recombinant Turkey Hepatitis Virus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P166-Tg001-Ab01,GMP-VT-P166-Tg001-Ab02
Pathogen	Turkey Hepatitis Virus
Product Name	Anti-Turkey Hepatitis Virus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Turkey Hepatitis Virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Turkey Hepatitis Virus antibodies in Turkey Hepatitis Virus level test of animal Turkey infectious disease with Turkey Hepatitis.
Product description	Anti-Turkey Hepatitis Virus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Turkey Hepatitis Virus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P166-Tg001-Ab03,GMP-VT-P166-Tg001-Ab04
Pathogen	Turkey Hepatitis Virus
Product Name	Anti-Turkey Hepatitis Virus human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Turkey Hepatitis Virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Turkey Hepatitis Virus antibodies in Turkey Hepatitis Virus level test of animal Turkey infectious disease with Turkey Hepatitis.
Product description	Anti-Turkey Hepatitis Virus mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Turkey Hepatitis Virus (Avihepavirus turcicus): An In-Depth Examination

Introduction:

Turkey Hepatitis Virus, scientifically known as Avihepavirus turcicus, is a hypothetical viral pathogen that affects domestic turkeys (Meleagris gallopavo). This virus is classified within the Hepadnaviridae family, a group encompassing viruses well-known for their ability to induce hepatitis in various avian species. In this comprehensive overview, we will delve into the classification, structural attributes, hosts affected, associated diseases, and diagnostic methods pertinent to the Turkey Hepatitis Virus.

Pathogen Classification:

Turkey Hepatitis Virus is a member of the Hepadnaviridae family, which categorizes it as a DNA virus. Specifically, it falls under the Hepadnavirus genus. This classification is significant, as it aligns the virus with the likes of Hepatitis B Virus, which affects humans. Hepadnaviruses are characterized by their unique partially double-stranded DNA genomes and share similarities in genomic organization and replication strategies.

Pathogen Structure:

The primary genetic entity of Turkey Hepatitis Virus is the Hepatitis B Virus Core gene (HBc). This gene encodes the core protein, which plays a crucial role in viral capsid formation and the encapsidation of the viral genome. In addition to HBc, the virus features the Hepatitis B Virus Surface Antigen (HBsAg). This surface antigen is a vital component, as it is responsible for viral attachment to host cells and is a primary target for immune responses in infected turkeys.

Hosts Infected by the Pathogen:

The host species for Turkey Hepatitis Virus is the domestic turkey, Meleagris gallopavo. This avian species is highly susceptible to infection by the virus. When infected, turkeys can develop a condition commonly referred to as Turkey Hepatitis or Avian Hepatitis. The impact of this disease can be significant, particularly on the liver. The virus can lead to hepatic damage and disrupt normal liver function, causing a range of clinical symptoms.

Disease Characteristics:

Turkey Hepatitis, also known as Avian Hepatitis, is the primary pathology associated with the Turkey Hepatitis Virus. This disease is characterized by inflammation and damage to the liver tissue. Clinical signs may include jaundice, lethargy, decreased egg production in laying hens, and, in severe cases, mortality. The liver is the central organ affected, and histopathological examination often reveals characteristic lesions and hepatocellular necrosis.

Diagnostic Methods:

Accurate diagnosis of Turkey Hepatitis Virus is pivotal for disease management and surveillance. Several diagnostic methods are utilized to detect the virus in affected turkeys:

Serological Tests:

Enzyme-Linked Immunosorbent Assay (ELISA): ELISA tests target the detection of the Hepatitis B Virus Surface Antigen (HBsAg) and anti-HBs antibodies in turkey serum, providing a serological profile of infection.

Western Blot Analysis: Western blot is employed to confirm the presence of viral proteins, further validating the infection.

Molecular Tests:

Polymerase Chain Reaction (PCR): PCR assays focus on specific regions of the viral genome, such as the S gene (HBsAg) and the core gene (HBc). These tests are essential for the detection of viral DNA.

Reverse Transcription PCR (RT-PCR): RT-PCR is used to identify viral RNA, indicating active infection, especially in cases of acute disease.

Histopathology:

Liver Biopsy: Liver biopsy is conducted to obtain tissue samples for histological examination. It allows for the assessment of liver damage and the identification of characteristic lesions associated with Turkey Hepatitis.

Immunohistochemistry:

Immunohistochemical techniques facilitate the visualization of viral antigens, such as HBcAg, within liver tissue sections. This method aids in confirming the presence of the virus in affected tissues.

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