Infectious Bursal Disease Virus antibody and antigen (recombinant protein)

Diagnostic anti-Infectious Bursal Disease Virus antibodies pairs and antigen for animal health (animal Chicken infectious disease Infectious bursal disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P171-Ag01 Recombinant Infectious Bursal Disease Virus protein $3090.00
GMP-VT-P171-Ab01 Anti-Infectious Bursal Disease Virus mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P171-Ab02 Anti-Infectious Bursal Disease Virus mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P171-Ag01
Product Name Recombinant Infectious Bursal Disease Virus protein
Pathogen Infectious Bursal Disease Virus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Infectious Bursal Disease Virus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Infectious Bursal Disease Virus level test of animal Chicken infectious disease with Infectious bursal disease.
Tag His
Product description Recombinant Infectious Bursal Disease Virus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P171-Ab01,GMP-VT-P171-Ab02
Pathogen Infectious Bursal Disease Virus
Product Name Anti-Infectious Bursal Disease Virus mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Infectious Bursal Disease Virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bursal Disease Virus antibodies in Infectious Bursal Disease Virus level test of animal Chicken infectious disease with Infectious bursal disease.
Product description Anti-Infectious Bursal Disease Virus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bursal Disease Virus antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen


    Duck Hepatitis Virus (DHAV): A Comprehensive Scientific Overview

    Introduction:

    Duck Hepatitis Virus (DHAV), scientifically known as Duck Hepatitis A Virus (DHAV), is a significant pathogen that primarily affects avian species, with ducks being particularly susceptible. This virus belongs to the Picornaviridae family, a group of small, non-enveloped, positive-sense, single-stranded RNA viruses. Within this family, DHAV is classified into three serotypes, with DHAV-1 being the most prevalent and virulent strain. This comprehensive overview explores various aspects of DHAV, from its classification and structure to its associated diseases and diagnostic methods.

    Classification:

    DHAV is a viral pathogen and belongs to the order Picornavirales. It is essential to note that viruses are distinct entities that lack cellular structures, and hence, they do not fall into the categories of prokaryotic or eukaryotic life forms. Viruses are often classified within the viral kingdom due to their unique characteristics, primarily consisting of genetic material enclosed within a protein coat. DHAV is a prime example of this classification, comprising RNA as its genetic material.

    Structure:

    The structure of DHAV is a critical aspect in understanding its virulence and pathogenicity. DHAV's structural components are primarily composed of genetic material and viral proteins. The genomic structure of DHAV consists of a single-stranded, positive-sense RNA molecule. This RNA genome encodes the information required for viral replication and assembly within the host organism.

    The viral capsid, responsible for protecting the genetic material and facilitating host cell infection, is composed of various structural proteins. Notably, VP0, VP1, and VP3 are the main constituents of the capsid. These proteins play pivotal roles in the virion assembly process, ensuring that the virus maintains its integrity and successfully infects host cells. Understanding the structural aspects of DHAV is crucial for the development of diagnostic and therapeutic interventions.

    Hosts Infected and Associated Diseases:

    DHAV predominantly infects avian species, with ducks being particularly susceptible. Young ducklings are most vulnerable to infection, which can result in severe and often fatal consequences. The disease induced by DHAV infection is recognized as Duck Viral Enteritis (DVE), also commonly referred to as Duck Hepatitis. DVE is characterized by a range of clinical signs and pathological changes, including severe enteric and hepatic lesions, leading to mortality rates that can approach 100% in affected ducklings. The economic impact of DHAV on the duck farming industry is substantial due to its devastating effects on duck populations.

    Diagnostic Methods:

    Accurate and timely diagnosis of DHAV is essential for controlling outbreaks and implementing effective preventive measures. Several diagnostic methods are employed in the detection of DHAV:

    Polymerase Chain Reaction (PCR): Molecular assays, such as PCR, are widely used to detect the presence of DHAV RNA in infected tissue samples. PCR targets specific genomic regions, often the 5' untranslated region or the VP1 gene. This method provides high sensitivity and specificity, allowing for early detection and differentiation of DHAV strains.

    Enzyme-Linked Immunosorbent Assay (ELISA): ELISA tests are valuable for identifying DHAV-specific antibodies in duck serum samples. The presence of antibodies indicates previous exposure to the virus and may aid in surveillance and serological studies.

    Virus Isolation: DHAV can be isolated and identified through in vitro cell culture techniques. The isolation of the virus is a fundamental step in studying its characteristics and in developing vaccines or antiviral drugs.

    Histopathology: Microscopic examination of infected tissues reveals characteristic histological lesions associated with DHAV infection. Pathologists can identify cellular changes and tissue damage that are indicative of the presence of the virus. This method contributes to the confirmation of diagnosis in affected ducks.

    Conclusion:

    Duck Hepatitis Virus (DHAV) is a significant pathogen in the avian world, particularly impacting duck populations. Its classification as a Picornavirus and its unique structural components make it a subject of interest in the field of virology. The disease it causes, Duck Viral Enteritis (DVE), can have severe consequences, both economically and ecologically. Accurate diagnostic methods, including PCR, ELISA, virus isolation, and histopathology, are crucial for managing and controlling DHAV outbreaks and for advancing research in virology. Further research into DHAV and the development of effective preventive and therapeutic measures remain critical in mitigating its impact on duck populations.



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