Trichinella antibody and antigen (recombinant protein)

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Diagnostic anti-Trichinella antibodies pairs and antigen for animal health (animal Equine/Horse, Swine/Porcine/Pig infectious disease Trichinosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P234-Ag01	Recombinant Trichinella protein	$3090.00
GMP-VT-P234-Ab01	Anti-Trichinella mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P234-Ab02	Anti-Trichinella mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P234-Ag01
Product Name	Recombinant Trichinella protein
Pathogen	Trichinella
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Trichinella antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Trichinella level test of animal Equine/Horse, Swine/Porcine/Pig infectious disease with Trichinosis.
Tag	His
Product description	Recombinant Trichinella proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P234-Ab01,GMP-VT-P234-Ab02
Pathogen	Trichinella
Product Name	Anti-Trichinella mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Trichinella antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Trichinella antibodies in Trichinella level test of animal Equine/Horse, Swine/Porcine/Pig infectious disease with Trichinosis.
Product description	Anti-Trichinella mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Trichinella antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen

Turkey Rhinotracheitis (Avian Metapneumovirus - aMPV)

Turkey Rhinotracheitis (TRT), caused by Avian Metapneumovirus (aMPV), is a significant respiratory disease that primarily affects turkeys, albeit it can also impact chickens and other avian species. Understanding this pathogen, its classification, structure, host range, associated diseases, and diagnostic methods is crucial for effective disease management and control within the poultry industry.

Pathogen Classification:

Avian Metapneumovirus is a member of the Pneumoviridae family, within the Metapneumovirus genus. This virus is classified as a non-segmented negative-sense RNA virus. Its genome encodes several essential proteins, including the Fusion (F) protein, Attachment (G) protein, Nucleoprotein (N), Matrix (M2) protein, and Polymerase (L) protein.

The Fusion (F) protein is a key player in viral entry, as it facilitates the fusion of viral and cellular membranes. The Attachment (G) protein is involved in viral attachment and subsequent infection. The Nucleoprotein (N) is crucial for packaging the viral genome, while the Matrix (M2) protein aids in virion assembly. The Polymerase (L) protein is essential for viral replication and transcription.

Hosts and Associated Diseases:

aMPV primarily affects turkeys (Meleagris gallopavo). When it infects a flock, it can lead to the onset of Turkey Rhinotracheitis (TRT). This disease is characterized by various clinical signs, including nasal discharge, coughing, and tracheal lesions. Turkeys affected by TRT may exhibit respiratory distress, which can result in reduced production and increased mortality in severe cases.

In chickens and other avian species, aMPV infection may lead to respiratory symptoms, although these symptoms are generally milder compared to turkeys. This variation in the severity of the disease across different hosts underscores the importance of understanding host-pathogen interactions and the potential economic impact on the poultry industry.

Diagnostic Methods:

Accurate and timely diagnosis of aMPV infections is crucial for disease management and prevention. The primary diagnostic approach involves nucleic acid testing, with Polymerase Chain Reaction (PCR) being a widely used method. These diagnostic methods target specific regions of the aMPV genome for detection and differentiation, primarily focusing on the Fusion (F) and Nucleoprotein (N) genes.

Reverse Transcription PCR (RT-PCR) is employed to amplify viral RNA, making it possible to detect and quantify the presence of aMPV in clinical samples. This approach offers high sensitivity and specificity, allowing for the reliable identification of infected birds.

Additional diagnostic methods may include serological assays, such as enzyme-linked immunosorbent assays (ELISA), which detect antibodies against aMPV in the serum of infected birds. These serological tests can provide information about the prevalence of past infections in a flock.

It's important to note that ongoing research may lead to the development of more advanced diagnostic methods and tools, emphasizing the dynamic nature of disease management within the poultry industry.

In conclusion, Turkey Rhinotracheitis, caused by Avian Metapneumovirus (aMPV), is a significant concern for the poultry industry. Understanding the virus's classification, structure, host range, associated diseases, and diagnostic methods is essential for disease control and management. With the use of advanced diagnostic techniques, it is possible to detect and monitor aMPV infections, ultimately aiding in the development of strategies to reduce the economic impact of this pathogen on poultry production.

For the most up-to-date information on aMPV and the latest diagnostic methods, it is advisable to consult the most recent scientific literature and research in the field of avian diseases.

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