Candida albicans antibody and antigen (recombinant protein)

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Diagnostic anti-Candida albicans antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease Candidiasis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P268-Tg001-Ag01	Recombinant Candida albicans protein	$3090.00
GMP-VT-P268-Tg001-Ab01	Anti-Candida albicans mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P268-Tg001-Ab02	Anti-Candida albicans mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P268-Tg001-Ab03	Anti-Candida albicans human monoclonal antibody (mAb)	$3090.00
GMP-VT-P268-Tg001-Ab04	Anti-Candida albicans human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P268-Tg001-Ag01
Product Name	Recombinant Candida albicans protein
Pathogen	Candida albicans
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Candida albicans antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Candida albicans level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with Candidiasis.
Tag	His
Product description	Recombinant Candida albicans proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P268-Tg001-Ab01,GMP-VT-P268-Tg001-Ab02
Pathogen	Candida albicans
Product Name	Anti-Candida albicans mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Candida albicans antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Candida albicans antibodies in Candida albicans level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with Candidiasis.
Product description	Anti-Candida albicans mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Candida albicans antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P268-Tg001-Ab03,GMP-VT-P268-Tg001-Ab04
Pathogen	Candida albicans
Product Name	Anti-Candida albicans human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Candida albicans antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Candida albicans antibodies in Candida albicans level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with Candidiasis.
Product description	Anti-Candida albicans mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Candida albicans: A Comprehensive Scientific Exploration

Introduction:

Candida albicans, an opportunistic fungal pathogen, occupies a pivotal position in microbiological research due to its relevance in human health and disease. This article aims to provide an in-depth scientific examination of Candida albicans, spanning taxonomy, structural features, pathogenicity, host-pathogen interactions, associated diseases, and diagnostic methodologies. By presenting this multifaceted exploration, we aim to offer a comprehensive and authoritative resource, enhancing its visibility in Google search results for the benefit of researchers, healthcare professionals, and curious individuals seeking a profound understanding of this yeast species.

1. Taxonomy and Classification:

The taxonomy of Candida albicans is intricate and warrants detailed scrutiny. Classified within the kingdom Fungi, phylum Ascomycota, and the class Saccharomycetes, it belongs to the Candida genus at the family level. The species designation is Candida albicans. This precise taxonomic placement is crucial for elucidating evolutionary relationships and understanding the genetic makeup of this organism.

2. Structural Features:

A deeper understanding of Candida albicans requires an exploration of its structural features, which significantly influence its pathogenicity. The intricate examination includes:

Cell Wall Composition: The cell wall of Candida albicans is a dynamic structure comprising glucans, mannans, and proteins. This section delves into the complexities of cell wall architecture, emphasizing its role in interactions with the host immune system.

Candida albicans Morphology: Candida albicans is dimorphic, meaning it can exist in two different forms: yeast and hyphal. This morphological plasticity is crucial for its pathogenicity. In the yeast form, it is less invasive, while in the hyphal form, it can penetrate tissues and evade the host immune system. This section provides insights into the genetic regulation of these morphological transitions.

Virulence Factors: The arsenal of virulence factors possessed by Candida albicans contributes to its pathogenic potential. A detailed discussion of factors such as secreted aspartyl proteases (SAPs), which degrade host tissues, and phospholipases, which disrupt host cell membranes, sheds light on their functions and implications in the context of infection. These factors play a critical role in the ability of Candida albicans to cause disease.

3. Host-Pathogen Interactions and Associated Diseases:

Understanding the intricate interplay between Candida albicans and its host is crucial for unraveling the spectrum of diseases associated with this organism. This section addresses:

Host Range: While Candida albicans primarily targets humans, it can also infect other mammals, underscoring its adaptability. The ability to infect a broad range of hosts is influenced by its ability to adapt to various environmental conditions within the host.

Disease Spectrum: The diseases attributed to Candida albicans are diverse and can range from superficial mucosal infections like oral thrush and vaginal yeast infections to invasive candidiasis, which can lead to severe systemic infections with life-threatening consequences. This section provides a comprehensive overview of these diseases, emphasizing their clinical manifestations and the factors that predispose individuals to Candida albicans infections.

Immunocompromised Hosts: Immunocompromised individuals, such as those with HIV/AIDS, cancer patients undergoing chemotherapy, or organ transplant recipients on immunosuppressive drugs, are particularly susceptible to Candida albicans infections. This section elucidates the heightened risks and clinical implications, emphasizing the importance of tailored therapeutic approaches and the role of the host immune system in preventing and controlling infections.

4. Diagnostic Approaches:

Accurate and timely diagnosis is paramount in managing Candida albicans infections. This section provides a meticulous overview of various diagnostic methodologies:

Microscopy: High-resolution microscopy techniques enable the visualization of yeast cells and hyphal structures, aiding in rapid diagnosis. Potassium hydroxide (KOH) preparations and Gram staining are commonly used methods to visualize Candida albicans under the microscope.

Culture-Based Methods: The traditional yet essential approach of culturing Candida albicans provides valuable insights into its growth characteristics and susceptibility patterns. Sabouraud agar and chromogenic media are commonly used culture mediums for isolating and identifying Candida species.

Molecular Techniques: Nucleic acid-based methods, including polymerase chain reaction (PCR) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), offer precise identification, facilitating targeted therapeutic interventions. PCR allows for the amplification of specific Candida DNA regions, aiding in rapid and accurate identification. MALDI-TOF MS is a powerful tool that can rapidly identify Candida species based on their protein profiles.

Immunoassays: Enzyme immunoassays and serological tests play a pivotal role in detecting Candida antigens and antibodies in patient samples. Enzyme-linked immunosorbent assay (ELISA) and immunodiffusion tests are commonly used immunoassays for diagnosing Candida infections. These tests detect specific antibodies or antigens produced in response to Candida infection.

Conclusion:

Candida albicans is a versatile and complex fungal species with significant implications for human health. This comprehensive scientific exploration has delved into its taxonomy, structural features, pathogenicity, host interactions, associated diseases, and diagnostic methods, offering a nuanced understanding of this intriguing organism. As research on Candida albicans continues to evolve, this resource provides a foundation for further inquiry and a valuable reference for clinicians, researchers, and the curious alike, ensuring that the profound intricacies of Candida albicans remain accessible and well-understood.

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