Porcine Parvovirus antibody and antigen (recombinant protein)

Diagnostic anti-Porcine Parvovirus antibodies pairs and antigen for animal health (animal Swine/Porcine/Pig infectious disease reproductive failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Swine/Porcine/Pig disease testing products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P292-Ag01 Recombinant Porcine Parvovirus protein $3090.00
GMP-VT-P292-Ab01 Anti-Porcine Parvovirus mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P292-Ab02 Anti-Porcine Parvovirus mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P292-Ag01
Product Name Recombinant Porcine Parvovirus protein
Pathogen Porcine Parvovirus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Porcine Parvovirus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Porcine Parvovirus level test of animal Swine/Porcine/Pig infectious disease with reproductive failure.
Tag His
Product description Recombinant Porcine Parvovirus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P292-Ab01,GMP-VT-P292-Ab02
Pathogen Porcine Parvovirus
Product Name Anti-Porcine Parvovirus mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Porcine Parvovirus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine Parvovirus antibodies in Porcine Parvovirus level test of animal Swine/Porcine/Pig infectious disease with reproductive failure.
Product description Anti-Porcine Parvovirus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine Parvovirus antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen


    Porcine Parvovirus, or PPV, is a highly infectious and economically important pathogen of pigs. PPV infection causes severe enteritis or inflammation of the small intestine in young pigs. The disease can occur as early as 10 days after birth and can result in significant morbidity and mortality rates. Additionally, PPV infection leads to decreased weight gain, which can lead to substantial economic losses in the pig farming industry.

    PPV belongs to the family Parvoviridae, which contains small, non-enveloped viruses with single-stranded DNA genomes. PPV has a simple structure, consisting of an icosahedral capsid enclosing its genome. The capsid is composed of two major proteins, VP1 and VP2, that are encoded by the viral genome. VP2 forms the outer surface of the capsid and mediates viral attachment and entry into host cells. VP1 is located on the interior surface of the capsid and is involved in the packaging of the viral genome.

    PPV primarily infects domestic pigs and wild boars. The virus is shed in feces and can persist in the environment for extended periods, making it highly contagious and easy to spread between animals. The virus infects cells in the pig's intestinal epithelium, leading to the development of enteritis. Infection can be asymptomatic or cause varying degrees of clinical disease, including diarrhea, vomiting, dehydration, and weight loss. In severe cases, death can occur due to secondary infections or electrolyte imbalances.

    Effective diagnosis of PPV infection is essential for efficient disease control and prevention. Various diagnostic methods are available for detecting PPV antigens or DNA in fecal samples, blood samples, or tissues from infected animals. Serological tests like enzyme-linked immunosorbent assays (ELISA) detect antibodies against PPV in blood samples, indicating previous exposure to the virus. PCR-based assays detect viral DNA in fecal samples, providing a sensitive and specific method for detecting active infection. Immunohistochemistry can be used to detect PPV antigens in tissues from infected animals, providing evidence of active viral replication.

    Prevention of PPV infection relies on a combination of immunization and management practices. Vaccination with inactivated or attenuated virus is an effective method for reducing the incidence and severity of disease. Additionally, good biosecurity measures can prevent the introduction and spread of the virus between farms. These include preventing contact between infected and susceptible pigs, disinfection of contaminated areas, and proper manure disposal.

    In conclusion, Porcine Parvovirus is a significant pathogen that poses a threat to pig farming globally. Its unique structure, genetic material, and host specificity make it important to have reliable diagnostic methods for efficient control and prevention of infection. Effective vaccination and management practices are essential for mitigating the impact of this disease on pig health and economic losses within the pig industry.



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