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Genemedi produces core diagnostic ingredients for test of Cardiovascular disease(hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy. ) and related syndrome.

GeneMedi offers paired diagnostics grade cardiac troponin T (cTnT) antibodies (monoclonal antibody,mab) and antigens for Cardiovascular disease(hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy. ) rapid test kit of cardiac troponin T (cTnT) testing in standard substance, positive control, ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

All the antibodies and antigens for Cardiovascular disease(hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy. ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used as positive control.

cTnT) is a protein that in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration.As part of the Troponin complex, the function of cTnT is to regulate muscle contraction. The N-terminal region of TnT that strongly binds actin most likely moves with Tm and actin during strong myosin crossbridge binding and force generation. This region is likely involved in the transduction of cooperativity down the thin filament.[14] The C-terminal region of TnT constitutes part of the globular troponin complex domain, and participates in employing the calcium sensitivity of strong myosin crossbridge binding to the thin filament.[15]Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with restrictive[16] and dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.[17] Mutations of this gene may be associated with mild or absent hypertrophy and predominant restrictive disease, with a high risk of sudden cardiac death.[16] Advancement to dilated cardiomyopathy may be more rapid in patients with TNNT2 mutations than in those with myosin heavy chain mutations.



Order information

Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-h-cTnT-Ag01-1mg 1mg 3090
GMP-h-cTnT-Ag01-10mg 10mg 21890
GMP-h-cTnT-Ag01-100mg 100mg 148000
GMP-h-cTnT-Ab01-1mg 1mg 1953
GMP-h-cTnT-Ab01-10mg 10mg 13671
GMP-h-cTnT-Ab01-100mg 100mg 95697
GMP-h-cTnT-Ab02-1mg 1mg 1953
GMP-h-cTnT-Ab02-10mg 10mg 13671
GMP-h-cTnT-Ab02-100mg 100mg 95697
GMP-h-cTnT-Ag/Ab-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Cat No. of Pruducts GMP-h-cTnT-Ag01
Product Name Recombinant human cTnT Protein
Target cardiac troponin T (cTnT)
Alias of Target/Biomarker CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation cardiac troponin T (cTnT) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in cTnT level test of Cardiovascular disease(hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy. ) and related syndrome evaluation.
Tag His
Products description Recombinant Human cardiac troponin T (cTnT) protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-cTnT-Ab01, GMP-h-cTnT-Ab02
Product Name Anti-human cTnT mouse monoclonal antibody (mAb)
Target cardiac troponin T (cTnT)
Alias of Target/Biomarker CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT
Expression platform Hybridoma
Isotypes Mouse IgG
Bioactivity validation Human cardiac troponin T (cTnT) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other cardiac troponin T (cTnT) antibodies in cTnT level test of Cardiovascular disease (hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy. ) and related syndrome evaluation.
Tag mFc
Products description Anti-Human cardiac troponin T (cTnT) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other cardiac troponin T (cTnT) antibodies.
Reconized/Reactive Species mouse
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.