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Human STAT3/ADMIO/ ADMIO1 ORF/cDNA clone-Lentivirus plasmid (NM_139276.2)
Pre-made Human STAT3/ADMIO/ ADMIO1 Lentiviral expression plasmid for STAT3 lentivirus packaging, STAT3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.
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Product information
| Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
|---|---|---|---|
| pGMLV000030 | Human STAT3 Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
| GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
| High Quality (HQ) Grade | |||
| Seed | 5ug |
Product Description
| Catalog ID | pGMLV000030 |
| Gene Name | STAT3 |
| Accession Number | NM_139276.2 |
| Gene ID | 6774 |
| Species | Human |
| Product Type | Lentivirus plasmid (overexpression) |
| Insert Length | 2313 bp |
| Gene Alias | ADMIO, ADMIO1, APRF, HIES |
| Fluorescent Reporter | mCherry |
| Mammalian Cell Selection | Puromyocinmyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T29130-Ab | Anti-STAT3 monoclonal antibody |
| Target Antigen | GM-Tg-g-T29130-Ag | STAT3 protein |
| ORF Viral Vector | pGMLV000030 | Human STAT3 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000031 | Human STAT3 Lentivirus plasmid |
| ORF Viral Vector | pGMLV001992 | Human STAT3 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000253 | Rat Stat3 Adenovirus plasmid |
| ORF Viral Vector | pGMAD000377 | Human STAT3 Adenovirus plasmid |
| ORF Viral Vector | pGMAD000541 | Rat Stat3 Adenovirus plasmid |
| ORF Viral Vector | pGMPC000002 | Human STAT3 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | pGMPC000158 | Human STAT3 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | pGMPC000417 | Human STAT3 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLV000030 | Human STAT3 Lentivirus particle |
| ORF Viral Vector | vGMLV000031 | Human STAT3 Lentivirus particle |
| ORF Viral Vector | vGMLV001992 | Human STAT3 Lentivirus particle |
| ORF Viral Vector | vGMAD000253 | Rat Stat3 Adenovirus particle |
| ORF Viral Vector | vGMAD000377 | Human STAT3 Adenovirus particle |
| ORF Viral Vector | vGMAD000541 | Rat Stat3 Adenovirus particle |
Target information
| Target ID | GM-T29130 |
| Target Name | STAT3 |
| Gene ID | 6774, 20848, 574128, 25125, 101095698, 490967, 508541, 100034011 |
| Gene Symbol and Synonyms | 1110034C02Rik,ADMIO,ADMIO1,APRF,HIES,STAT3 |
| Uniprot Accession | P40763 |
| Uniprot Entry Name | STAT3_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000168610 |
| Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. [provided by RefSeq, Aug 2020]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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