Human VIP/PHM27 ORF/cDNA clone-Lentivirus plasmid (NM_003381.4)

Cat. No.: pGMLV000792
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human VIP/PHM27 Lentiviral expression plasmid for VIP lentivirus packaging, VIP lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000792
Gene Name VIP
Accession Number NM_003381.4
Gene ID 7432
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 513 bp
Gene Alias PHM27
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGACACCAGAAATAAGGCCCAGCTCCTTGTGCTCCTGACTCTTCTCAGTGTGCTCTTCTCACAGACTTCGGCATGGCCTCTTTACAGGGCACCTTCTGCTCTCAGGTTGGGTGACAGAATACCCTTTGAGGGAGCAAATGAACCTGATCAAGTTTCATTAAAAGAAGACATTGACATGTTGCAAAATGCATTAGCTGAAAATGACACACCCTATTATGATGTATCCAGAAATGCCAGGCATGCTGATGGAGTTTTCACCAGTGACTTCAGTAAACTCTTGGGTCAACTTTCTGCCAAAAAGTACCTTGAGTCTCTTATGGGAAAACGTGTTAGCAGTAACATCTCAGAAGACCCTGTACCAGTCAAACGTCACTCAGATGCAGTCTTCACTGACAACTATACCCGCCTTAGAAAACAAATGGCTGTAAAGAAATATTTGAACTCAATTCTGAATGGAAAGAGGAGCAGTGAGGGAGAATCTCCCGACTTTCCAGAAGAGTTAGAAAAATGA
ORF Protein Sequence MDTRNKAQLLVLLTLLSVLFSQTSAWPLYRAPSALRLGDRIPFEGANEPDQVSLKEDIDMLQNALAENDTPYYDVSRNARHADGVFTSDFSKLLGQLSAKKYLESLMGKRVSSNISEDPVPVKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGESPDFPEELEK

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T88213-Ab Anti-VIP/ PHM27 functional antibody
    Target Antigen GM-Tg-g-T88213-Ag VIP protein
    ORF Viral Vector pGMLV000792 Human VIP Lentivirus plasmid
    ORF Viral Vector pGMAP000149 Human VIP Adenovirus plasmid
    ORF Viral Vector vGMLV000792 Human VIP Lentivirus particle
    ORF Viral Vector vGMAP000149 Human VIP Adenovirus particle


    Target information

    Target ID GM-T88213
    Target Name VIP
    Gene ID 7432, 22353, 703566, 117064, 101101640, 484038, 280956, 100060155
    Gene Symbol and Synonyms PHM27,VIP,vip/phi27
    Uniprot Accession P01282
    Uniprot Entry Name VIP_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000146469
    Target Classification Tumor-associated antigen (TAA)

    The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]



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