Human PTP4A3/PRL-3/PRL-R ORF/cDNA clone-Lentivirus plasmid (NM_007079.3)

Cat. No.: pGMLV001318
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PTP4A3/PRL-3/PRL-R Lentiviral expression plasmid for PTP4A3 lentivirus packaging, PTP4A3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV001318
Gene Name PTP4A3
Accession Number NM_007079.3
Gene ID 11156
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 447 bp
Gene Alias PRL-3,PRL-R,PRL3
Fluorescent Reporter mCherry
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCTCGGATGAACCGCCCGGCCCCGGTGGAGGTGAGCTACAAACACATGCGCTTCCTCATCACCCACAACCCCACCAACGCCACGCTCAGCACCTTCATTGAGGACCTGAAGAAGTACGGGGCTACCACTGTGGTGCGTGTGTGTGAAGTGACCTATGACAAAACGCCGCTGGAGAAGGATGGCATCACCGTTGTGGACTGGCCGTTTGACGATGGGGCGCCCCCGCCCGGCAAGGTAGTGGAAGACTGGCTGAGCCTGGTGAAGGCCAAGTTCTGTGAGGCCCCCGGCAGCTGCGTGGCTGTGCACTGCGTGGCGGGCCTGGGCCGGAAGCGCCGCGGAGCCATCAACAGCAAGCAGCTCACCTACCTGGAGAAATACCGGCCCAAACAGAGGCTGCGGTTCAAAGACCCACACACGCACAAGACCCGGTGCTGCGTTATGTAG
ORF Protein Sequence MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T78019-Ab Anti-PRL-3 monoclonal antibody
    Target Antigen GM-Tg-g-T78019-Ag PRL-3/PTP4A3 protein
    ORF Viral Vector pGMLP000864 Human PTP4A3 Lentivirus plasmid
    ORF Viral Vector pGMLV001318 Human PTP4A3 Lentivirus plasmid
    ORF Viral Vector vGMLP000864 Human PTP4A3 Lentivirus particle
    ORF Viral Vector vGMLV001318 Human PTP4A3 Lentivirus particle


    Target information

    Target ID GM-T78019
    Target Name PRL-3
    Gene ID 11156, 19245, 693703, 362930, 101096639, 606961, 100137722, 100058296
    Gene Symbol and Synonyms pPtp4a3,PRL-3,PRL-R,PRL3,PTP4A3
    Uniprot Accession O75365
    Uniprot Entry Name TP4A3_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000184489
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]



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