Human TXNDC12/AG1/AGR1 ORF/cDNA clone-Lentivirus plasmid (NM_015913)

Cat. No.: pGMLV001789
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TXNDC12/AG1/AGR1 Lentiviral expression plasmid for TXNDC12 lentivirus packaging, TXNDC12 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV001789
Gene Name TXNDC12
Accession Number NM_015913
Gene ID 51060
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 519 bp
Gene Alias AG1,AGR1,ERP16,ERP18,ERP19,hAG-1,hTLP19,PDIA16,TLP19
Fluorescent Reporter Firefly luciferase
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGACGCGGCCTCGTCTCGGGGCCACCTGTTTGCTGGGCTTCAGTTTCCTGCTCCTCGTCATCTCTTCTGATGGACATAATGGGCTTGGAAAGGGTTTTGGAGATCATATTCATTGGAGGACACTGGAAGATGGGAAGAAAGAAGCAGCTGCCAGTGGACTGCCCCTGATGGTGATTATTCATAAATCCTGGTGTGGAGCTTGCAAAGCTCTAAAGCCCAAATTTGCAGAATCTACGGAAATTTCAGAACTCTCCCATAATTTTGTTATGGTAAATCTTGAGGATGAAGAGGAACCCAAAGATGAAGATTTCAGCCCTGACGGGGGTTATATTCCACGAATCCTTTTTCTGGATCCCAGTGGCAAGGTGCATCCTGAAATCATCAATGAGAATGGAAACCCCAGCTACAAGTATTTTTATGTCAGTGCCGAGCAAGTTGTTCAGGGGATGAAGGAAGCTCAGGAAAGGCTGACGGGTGATGCCTTCAGAAAGAAACATCTTGAAGATGAATTGTAA
ORF Protein Sequence METRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDPSGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T36419-Ab Anti-TXD12/ TXNDC12/ AG1 functional antibody
    Target Antigen GM-Tg-g-T36419-Ag TXNDC12 protein
    ORF Viral Vector pGMLP004211 Human TXNDC12 Lentivirus plasmid
    ORF Viral Vector pGMLV001789 Human TXNDC12 Lentivirus plasmid
    ORF Viral Vector vGMLP004211 Human TXNDC12 Lentivirus particle
    ORF Viral Vector vGMLV001789 Human TXNDC12 Lentivirus particle


    Target information

    Target ID GM-T36419
    Target Name TXNDC12
    Gene ID 51060, 66073, 712891, 298370, 101089631, 609843, 506991, 100062254
    Gene Symbol and Synonyms 0610040B21Rik,AG1,AGR1,ERP16,ERP18,ERP19,hAG-1,hTLP19,PDIA16,RGD1305960,TLP19,TXNDC12
    Uniprot Accession O95881
    Uniprot Entry Name TXD12_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000117862
    Target Classification Not Available

    This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]



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